Evidence map›Paper›PMID 38023160›Full record

ReviewFrontiers in oncology2023

The implication of next-generation sequencing in the diagnosis and clinical management of non-Hodgkin lymphomas.

Victor Tomacinschii, Adrian Mosquera Orgueira, Carlos Aliste Santos, Maria Robu, Sanda Buruiana, Maximo Francisco Fraga Rodriguez

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Victor TomacinschiiDepartment of Hematology, Nicolae Testemitanu State University of Medicine and Pharmacy, Chisinau, Moldova.
Adrian Mosquera OrgueiraUniversity Hospital of Santiago de Compostela, Servizo Galego de Saude (SERGAS), Santiago de Compostela, Spain.
Carlos Aliste SantosUniversity Hospital of Santiago de Compostela, Servizo Galego de Saude (SERGAS), Santiago de Compostela, Spain.
Maria RobuDepartment of Hematology, Nicolae Testemitanu State University of Medicine and Pharmacy, Chisinau, Moldova.
Sanda BuruianaDepartment of Hematology, Nicolae Testemitanu State University of Medicine and Pharmacy, Chisinau, Moldova.
Maximo Francisco Fraga RodriguezUniversity Hospital of Santiago de Compostela, Servizo Galego de Saude (SERGAS), Santiago de Compostela, Spain.
Nicolae Testemițanu State University of Medicine and Pharmacy · MDUniversidade de Santiago de Compostela · ESServicio Gallego de Salud · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Next generation sequencing (NGS) is a technology that broadens the horizon of knowledge of several somatic pathologies, especially in oncological and oncohematological pathology. In the case of NHL, the understanding of the mechanisms of tumorigenesis, tumor proliferation and the identification of genetic markers specific to different lymphoma subtypes led to more accurate classification and diagnosis. Similarly, the data obtained through NGS allowed the identification of recurrent somatic mutations that can serve as therapeutic targets that can be inhibited and thus reducing the rate of resistant cases. The article's purpose is to offer a comprehensive overview of the best ways of integrating of next-generation sequencing technologies for diagnosis, prognosis, classification, and selection of optimal therapy from the perspective of tailor-made medicine.

Indexed as

diagnosisgenomicslymphomasnext-generation sequencingnon-Hodgkin lymphomas

Identifiers

PMID38023160
PMCPMC10663367
OpenAlexW4388538597

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.