Evidence map›Paper›PMID 38023154›Full record

ArticleFrontiers in oncology2023

Cost items in melanoma patients by clinical characteristics and time from diagnosis.

Alessandra Buja, Claudia Cozzolino, Anna Zanovello, Ruggero Geppini, Andrea Miatton, Manuel Zorzi, Mariagiovanna Manfredi, Emanuela Bovo, Paolo Del Fiore, Saveria Tropea and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Alessandra BujaDepartment of Cardiologic, Vascular and Thoracic Sciences, and Public Health, University of Padua, Padua, Italy.
Claudia CozzolinoDepartment of Cardiologic, Vascular and Thoracic Sciences, and Public Health, University of Padua, Padua, Italy.
Anna ZanovelloDepartment of Cardiologic, Vascular and Thoracic Sciences, and Public Health, University of Padua, Padua, Italy.
Ruggero GeppiniDepartment of Cardiologic, Vascular and Thoracic Sciences, and Public Health, University of Padua, Padua, Italy.
Andrea MiattonDepartment of Cardiologic, Vascular and Thoracic Sciences, and Public Health, University of Padua, Padua, Italy.
Manuel ZorziVeneto Tumor Registry, Azienda Zero, Padua, Italy.
Mariagiovanna ManfrediDepartment of Cardiologic, Vascular and Thoracic Sciences, and Public Health, University of Padua, Padua, Italy.
Emanuela BovoVeneto Tumor Registry, Azienda Zero, Padua, Italy.
Paolo Del FioreSoft-Tissue, Peritoneum and Melanoma Surgical Oncology Unit, Veneto Institute of Oncology (IOV), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Padua, Italy.
Saveria TropeaSoft-Tissue, Peritoneum and Melanoma Surgical Oncology Unit, Veneto Institute of Oncology (IOV), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Padua, Italy.
Luigi dall'OlmoSoft-Tissue, Peritoneum and Melanoma Surgical Oncology Unit, Veneto Institute of Oncology (IOV), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Padua, Italy.
Carlo Riccardo RossiDepartment of Surgery, Oncology and Gastroenterology (DISCOG), University of Padua, Padua, Italy.
Simone MocellinSoft-Tissue, Peritoneum and Melanoma Surgical Oncology Unit, Veneto Institute of Oncology (IOV), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Padua, Italy.
Marco RastrelliSoft-Tissue, Peritoneum and Melanoma Surgical Oncology Unit, Veneto Institute of Oncology (IOV), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Padua, Italy.
Massimo RuggeVeneto Tumor Registry, Azienda Zero, Padua, Italy.
University of Padua · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITRegione del Veneto · ITIstituto Oncologico Veneto · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Costs related to the care of melanoma patients have been rising over the past few years due to increased disease incidence as well as the introduction of innovative treatments. The aim of this study is to analyse CMM cost items based on stage at diagnosis, together with other diagnostic and prognostic characteristics of the melanoma. Methods: Analyses were performed on 2,647 incident cases of invasive CMM that were registered in 2015 and 2017 in the Veneto Cancer Registry (RTV). Direct melanoma-related costs per patient were calculated for each year ranging from 2 years before diagnosis to 4 years after, and were stratified by cost items such as outpatient services, inpatient drug prescriptions, hospital admissions, hospice admissions, and emergency room treatment. Average yearly costs per patient were compared according to available clinical-pathological characteristics. Lastly, log-linear multivariable analysis was performed to investigate potential cost drivers among these clinical-pathological characteristics. Findings: Overall, the average direct costs related to melanoma are highest in the first year after diagnosis (€2,903) and then decrease over time. Hospitalization costs are 8 to 16 times higher in the first year than in subsequent years, while the costs of outpatient services and inpatient drugs decrease gradually over time. When stratified by stage it is observed that the higher expenditure associated with more advanced stages of CMM is mainly due to inpatient drug use. Conclusion: The results of the present study show that grouping patients according to tumour characteristics can improve our understanding of the different cost items associated with cutaneous malignant melanoma. CMM patients experience higher costs in the first year after diagnosis due to higher hospitalization and outpatient services. Policy makers should consider overall and stage-specific annual costs when allocating resources for the management of CMM patients.

Indexed as

cost of illnessdirect costshealthcare assessmenthealthcare services researchhealth economicsmelanomaspecific costs

Identifiers

PMID38023154
PMCPMC10666743
OpenAlexW4388554824

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.