Evidence map›Paper›PMID 38023107›Full record

ArticleInternational journal of biomaterials2023

Inhibition and Reduction of Biofilm Production along with Their Antibiogram Pattern among Gram-Negative Clinical Isolates.

Ojaswee Shrestha, Nabina Shrestha, Sadhana Khanal, Sushant Pokhrel, Sujina Maharjan, Tika Bahadur Thapa, Puspa Raj Khanal, Govardhan Joshi

Open access · goldAbstract read
In one paragraph

Article in International journal of biomaterials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ojaswee ShresthaDepartment of Laboratory Medicine, Manmohan Memorial Institute of Health Sciences, Kathmandu, Nepal.
Nabina ShresthaDepartment of Laboratory Medicine, Manmohan Memorial Institute of Health Sciences, Kathmandu, Nepal.
Sadhana KhanalDepartment of Laboratory Medicine, Manmohan Memorial Institute of Health Sciences, Kathmandu, Nepal.
Sushant PokhrelDepartment of Laboratory Medicine, Manmohan Memorial Institute of Health Sciences, Kathmandu, Nepal.ORCID https://orcid.org/0000-0001-9564-8405
Sujina MaharjanDepartment of Laboratory Medicine, Manmohan Memorial Institute of Health Sciences, Kathmandu, Nepal.
Tika Bahadur ThapaDepartment of Laboratory Medicine, Manmohan Memorial Institute of Health Sciences, Kathmandu, Nepal.ORCID https://orcid.org/0000-0001-7337-5602
Puspa Raj KhanalDepartment of Pathology, Sumeru Hospital Pvt Ltd, Lalitpur, Nepal.
Govardhan JoshiDepartment of Laboratory Medicine, Manmohan Memorial Institute of Health Sciences, Kathmandu, Nepal.ORCID https://orcid.org/0000-0003-3819-2303
Manmohan Memorial Institute of Health Sciences · NP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Bacterial biofilm is a significant virulence factor threatening patients, leading to chronic infections and economic burdens. Therefore, it is crucial to identify biofilm production, its inhibition, and reduction. In this study, we investigated biofilm production among Gram-negative isolates and assessed the inhibitory and reduction potential of ethylene diamine tetra acetic acid (EDTA) and dimethyl sulfoxide (DMSO) towards them. In addition, we studied the antimicrobial resistance pattern of the Gram-negative isolates. Methods: Bacterial isolation and identification was done using standard microbiological techniques, following the Clinical and Laboratory Standards Institute (CLSI) guideline, 28th edition. The Kirby-Bauer disk diffusion method was used to determine the antibiotic susceptibility pattern of the isolates, and Results: Among the 110 clinical isolates, 61.8% (68) were found to be multidrug resistant (MDR). 30% (33/110) of the isolates were extended-spectrum Conclusion: Isolates forming biofilm had a higher resistance rate and

Identifiers

PMID38023107
PMCPMC10673669
OpenAlexW4388775261

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.