Evidence map›Paper›PMID 38022871›Full record

ArticleAmerican journal of clinical and experimental immunology2023

Clinical analysis and methodological evaluation of syphilis infection in patients in a first-class tertiary hospital in Suzhou, China.

Sheng Zhang, Chen Ling, Zhongping Qian, Jingping Yin, Qingqin Tang, Ximeng Zhang, Yinjuan Shi, Bin Feng, Jie Ding, Qian Yang

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in American journal of clinical and experimental immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Sheng ZhangCentre of Clinical Laboratory, The First Affiliated Hospital of Soochow University Suzhou 215006, Jiangsu, China.
Chen LingCentre of Clinical Laboratory, The First Affiliated Hospital of Soochow University Suzhou 215006, Jiangsu, China.
Zhongping QianCentre of Clinical Laboratory, The First Affiliated Hospital of Soochow University Suzhou 215006, Jiangsu, China.
Jingping YinCentre of Clinical Laboratory, The First Affiliated Hospital of Soochow University Suzhou 215006, Jiangsu, China.
Qingqin TangCentre of Clinical Laboratory, The First Affiliated Hospital of Soochow University Suzhou 215006, Jiangsu, China.
Ximeng ZhangDepartment of Neurology, The First Affiliated Hospital of Soochow University Suzhou 215006, Jiangsu, China.
Yinjuan ShiDepartment of Dermatology, The First Affiliated Hospital of Soochow University Suzhou 215006, Jiangsu, China.
Bin FengCentre of Clinical Laboratory, The First Affiliated Hospital of Soochow University Suzhou 215006, Jiangsu, China.
Jie DingCentre of Clinical Laboratory, The First Affiliated Hospital of Soochow University Suzhou 215006, Jiangsu, China.
Qian YangCentre of Clinical Laboratory, The First Affiliated Hospital of Soochow University Suzhou 215006, Jiangsu, China.
Soochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the distribution and epidemiological characteristics of patients with syphilis in a first-class tertiary hospital and to evaluate the coincidence rate between chemiluminescence immunoassay (CLIA) and

methodsThe medical records of 247,501 outpatients and inpatients were retrospectively analyzed. TPPA was used to verify positive and suspected cases, and the coincidence rate between CLIA and TPPA was evaluated. Receiver operating characteristic (ROC) curve was used to determine optimal diagnostic thresholds.

resultsOf the 247,501 serum samples, 5,173 were detected positive for syphilis using CLIA, with a detection rate of 2.09% and a men-to-women ratio of 1.39. The chi-square test showed that sex and age were both factors that affected the detection rate (χ

conclusionsSyphilis is widely distributed in various hospital departments and primarily affects middle-aged and older individuals. For cases that have been initially screened as positive or suspicious, TPPA and other tests should be used for verification to avoid misdiagnosis and missed diagnosis.

Indexed as

diagnostic performanceepidemiologyserological screeningSyphilis

Identifiers

PMID38022871
PMCPMC10658164
OpenAlexW4389178785

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.