Association between IL-10 (at position -592) and IL-4 (at position -589) genotype polymorphism with atopic and non-atopic asthma in children.

Anahita Razaghian, Nima Parvaneh, Ali Akbar Amirzargar, Matineh Nirouei, Mohammad Gharagozlou

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In one paragraph

Article in American journal of clinical and experimental immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.2field-weighted citation impact, top 44% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

A study on the distribution of interleukin-10 gene polymorphisms and their association with febrile seizure susceptibility in children from the Wenzhou region, Zhejiang Province.Frontiers in public health · 2025
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Anahita RazaghianPediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences Tehran, Iran.

Nima ParvanehPediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences Tehran, Iran.

Ali Akbar AmirzargarMolecular Immunology Research Center, Tehran University of Medical Sciences Tehran, Iran.

Matineh NiroueiAlborz University of Medical Sciences Karaj, Iran.

Mohammad GharagozlouPediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences Tehran, Iran.

Jahrom University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesAsthma is the most prevalent respiratory disease, caused by chronic bronchial inflammation. Cytokines are known to play an important role in the pathophysiology of asthma. This study aimed to compare interleukin-4 (IL-4) and interleukin-10 (IL-10) gene polymorphisms between Iranian pediatric asthmatic patients and healthy controls and to investigate

methodsIn this prospective case-control study, a total of 95 unrelated pediatric asthmatic patients were recruited according to the Global Initiative for Asthma (GINA) criteria. The control group comprised two subgroups of 538 and 491 healthy individuals, undergoing

resultsThe findings indicated a significant difference in

conclusionThe

Indexed as

Asthmaatopygenetic polymorphisminterleukin-10 (IL-10)interleukin-4 (IL-4)single-nucleotide polymorphism

Identifiers

PMID38022870

PMCPMC10658160

OpenAlexW4389179184

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.