Evidence map›Paper›PMID 38022858›Full record

ArticleSAGE open medical case reports2023

Successful treatment of erosive lichen planus with Upadacitinib complicated by oral squamous cell carcinoma.

Fiona M Landells, Shaina Goudie, Jerry McGrath, Jamie Tibbo, Ian Dr Landells

Open access · goldAbstract readCase Reports
In one paragraph

Article in SAGE open medical case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Use of JAK Inhibitors in Lichen Planus: An Update.Medicina (Kaunas, Lithuania) · 2025
    Review
  5. Article
  6. Article
  7. Lichen Planus: What is New in Diagnosis and Treatment?American journal of clinical dermatology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Fiona M LandellsFaculty of Medicine, Memorial University of Newfoundland, St. John's, NL, Canada.ORCID https://orcid.org/0000-0002-1691-8604
Shaina GoudieDivision of Rheumatology, Memorial University of Newfoundland, St. John's, NL, Canada.
Jerry McGrathDivision of Gastroenterology, Memorial University of Newfoundland, St. John's, NL, Canada.
Jamie TibboDivision of Otolaryngology, Memorial University of Newfoundland, St. John's, NL, Canada.
Ian Dr LandellsDivision of Dermatology, Memorial University of Newfoundland, St. John's, NL, Canada.
Memorial University of Newfoundland · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Erosive lichen planus is a chronic auto-inflammatory disease which affects the stratified squamous epithelia resulting in painful ulcerations of both the skin and mucosal surfaces, and has a known malignant potential. Management of erosive lichen planus has proven to be difficult; however, recent reports of treatment with Janus kinase inhibitors such as Upadacitinib, are encouraging. This report outlines the third reported case of erosive lichen planus to be successfully treated with Upadacitinib in a 70-year-old woman with treatment-resistant disease. In addition, we report the complication of oral squamous cell carcinoma which became apparent once the extensive erosive lichen planus had healed. This case report highlights the importance of monitoring for mucosal squamous cell carcinoma in areas affected by erosive lichen planus, as squamous cell carcinoma can mimic the erosions of erosive lichen planus.

Indexed as

erosive lichen planussquamous cell carcinomaUpadacitinib

Identifiers

PMID38022858
PMCPMC10656796
OpenAlexW4388771763

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.