Evidence map›Paper›PMID 38022796›Full record

ArticleOrganic chemistry frontiers : an international journal of organic chemistry2023

Replication of synthetic recognition-encoded oligomers by ligation of trimer building blocks.

Diego Núñez-Villanueva, Christopher A Hunter

Abstract read
In one paragraph

Article in Organic chemistry frontiers : an international journal of organic chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Diego Núñez-VillanuevaYusuf Hamied Department of Chemistry, University of Cambridge Lensfield Road Cambridge CB2 1EW UK herchelsmith.orgchem@ch.cam.ac.uk.ORCID https://orcid.org/0000-0002-1005-1464
Christopher A HunterYusuf Hamied Department of Chemistry, University of Cambridge Lensfield Road Cambridge CB2 1EW UK herchelsmith.orgchem@ch.cam.ac.uk.ORCID https://orcid.org/0000-0002-5182-1859

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of methods for replication of synthetic information oligomers will underpin the use of directed evolution to search new chemical space. Template-directed replication of triazole oligomers has been achieved using a covalent primer in conjunction with non-covalent binding of complementary building blocks. A phenol primer equipped with an alkyne was first attached to a benzoic recognition unit on a mixed sequence template

Identifiers

PMID38022796
PMCPMC10661083

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.