Evidence map›Paper›PMID 38022639›Full record

ArticleFrontiers in immunology2023

Human CD79b

Melissa A Meyer, Huy Q Dinh, Ahmad Alimadadi, Daniel J Araujo, Nandini Chatterjee, Norma A Gutierrez, Yanfang Peipei Zhu, Emma L Hunter, Shu Liang, Gregory Seumois and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Target neutrophil heterogeneity and plasticity in cancer.Journal of hematology & oncology · 2025
    Review
  3. Sphingolipid metabolism and regulated cell death in malignant melanoma.Apoptosis : an international journal on programmed cell death · 2024
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 2 countries.

Melissa A Meyer *Center for Cancer Immunotherapy, La Jolla Institute for Immunology, La Jolla, CA, United States.
Huy Q Dinh *Center for Cancer Immunotherapy, La Jolla Institute for Immunology, La Jolla, CA, United States.
Ahmad AlimadadiCenter for Cancer Immunotherapy, La Jolla Institute for Immunology, La Jolla, CA, United States.
Daniel J AraujoCenter for Cancer Immunotherapy, La Jolla Institute for Immunology, La Jolla, CA, United States.
Nandini ChatterjeeCenter for Cancer Immunotherapy, La Jolla Institute for Immunology, La Jolla, CA, United States.
Norma A GutierrezCenter for Cancer Immunotherapy, La Jolla Institute for Immunology, La Jolla, CA, United States.
Yanfang Peipei ZhuCenter for Cancer Immunotherapy, La Jolla Institute for Immunology, La Jolla, CA, United States.
Emma L HunterCenter for Cancer Immunotherapy, La Jolla Institute for Immunology, La Jolla, CA, United States.
Shu LiangCenter for Cancer Immunotherapy, La Jolla Institute for Immunology, La Jolla, CA, United States.
Gregory SeumoisCenter for Cancer Immunotherapy, La Jolla Institute for Immunology, La Jolla, CA, United States.
William B KiossesMicroscopy and Histology Core Facility, La Jolla Institute for Immunology, La Jolla, CA, United States.
Sergio D CatzDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, United States.
Pandurangan VijayanandCenter for Cancer Immunotherapy, La Jolla Institute for Immunology, La Jolla, CA, United States.
Christian OttensmeierCenter for Cancer Immunotherapy, La Jolla Institute for Immunology, La Jolla, CA, United States.
Catherine C HedrickCenter for Cancer Immunotherapy, La Jolla Institute for Immunology, La Jolla, CA, United States.
La Jolla Institute for Immunology · USAugusta University · USScripps Research Institute · USUniversity of Liverpool · GBUniversity of Southampton · GBUniversity of Wisconsin–Madison · US

Funding

Transgenic & Gene-Targeting Shared ResourceP30CA168524 · NCI · UNIVERSITY OF KANSAS MEDICAL CENTER · PI ROY A. JENSEN · 2012 to 2026
$40.1M
Project 4: APOB-specific CD4 and CD8 T cells exacerbate atherosclerosisP01HL136275 · NHLBI · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI Catherine C Hedrick · 2017 to 2026
$25.5M
Neutrophil Survival and Demise During Inflammatory StatesP01HL152958 · NHLBI · SCRIPPS RESEARCH INSTITUTE, THE · PI CATZ, SERGIO DANIEL · 2021 to 2025
$12.4M
Vesicular trafficking mechanisms regulating granulocyte functionR01HL088256 · NHLBI · SCRIPPS RESEARCH INSTITUTE, THE · PI Sergio Daniel Catz · 2009 to 2026
$9.0M
Rheumatic Diseases Research Training GrantT32AR064194 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GARY S FIRESTEIN, Monica Guma · 2013 to 2026
$3.8M
Transcriptional Control of Monocyte DevelopmentR01HL134236 · NHLBI · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI HEDRICK, CATHERINE C · 2016 to 2019
$2.5M
Functions of Nonclassical Monocytes in the VasculatureR01CA202987 · NCI · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI HEDRICK, CATHERINE C · 2016 to 2020
$2.2M
Neutrophil heterogeneity and plasticity in wound healingR35GM150893 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Huy Quang Dinh · 2023 to 2026
$1.6M
Protective Role of Nonclassical Monocytes in Immunotherapies for Solid CancersU01CA224766 · NCI · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI HEDRICK, CATHERINE C, KAPLAN, ROSANDRA · 2018 to 2021
$1.4M
CyTOF Mass CytometerS10OD018499 · OD · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI CROTTY, SHANE P · 2014 to 2014
$802k
NCI NIH HHS P30 CA168524NCI NIH HHS R01 CA202987NCI NIH HHS U01 CA224766NHLBI NIH HHS P01 HL136275NHLBI NIH HHS P01 HL152958NHLBI NIH HHS R01 HL088256NHLBI NIH HHS R01 HL134236NIAMS NIH HHS T32 AR064194NIGMS NIH HHS R35 GM150893NIH HHS S10 OD018499
6 · The paper itself

Abstract

Purpose: Due to their abundance in the blood, low RNA content, and short lifespan, neutrophils have been classically considered to be one homogenous pool. However, recent work has found that mature neutrophils and neutrophil progenitors are composed of unique subsets exhibiting context-dependent functions. In this study, we ask if neutrophil heterogeneity is associated with melanoma incidence and/or disease stage. Experimental design: Using mass cytometry, we profiled melanoma patient blood for unique cell surface markers among neutrophils. Markers were tested for their predictiveness using flow cytometry data and random forest machine learning. Results: We identified CD79b Conclusion: Our work suggests that CD79b

Indexed as

Leukemia, Lymphocytic, Chronic, B-CellMelanomaAntigens, CD19B-LymphocytesHumansNeutrophilsAntigens, CD19biomarkerCD79bmass cytometrymelanomaneutrophils

Identifiers

PMID38022639
PMCPMC10643866
OpenAlexW4388083760

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.