Evidence map›Paper›PMID 38022478›Full record

ArticleAnnals of Indian Academy of Neurology

De Novo Movement Disorders Associated with COVID-19- A Systematic Review of Individual Patients.

Kanchana S Pillai, Shubham Misra, Govinda Siripurapu, Aminu Aliyar, Priyanka Bhat, Roopa Rajan, Achal Srivastava, Vinay Goyal, Anil Venkitachalam, Divya M Radhakrishnan

Open access · diamondAbstract read
In one paragraph

Article in Annals of Indian Academy of Neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Kanchana S PillaiDepartment of Neurology, Bombay Hospital Institute of Medical Sciences, Mumbai, Maharashtra, India.
Shubham MisraDepartment of Neurology, Yale University School of Medicine, New Haven, CT, USA.
Govinda SiripurapuDepartment of Neurology, All India Institute of Medical Sciences, New Delhi, India.
Aminu AliyarDepartment of Neurology, All India Institute of Medical Sciences, New Delhi, India.
Priyanka BhatDepartment of Neurology, All India Institute of Medical Sciences, New Delhi, India.
Roopa RajanDepartment of Neurology, All India Institute of Medical Sciences, New Delhi, India.
Achal SrivastavaDepartment of Neurology, All India Institute of Medical Sciences, New Delhi, India.
Vinay GoyalInstitute of Neurosciences, Medanta the Medicity, Gurugram, Haryana, India.
Anil VenkitachalamDepartment of Neurology, Lokmanya Tilak Municipal Medical College, Mumbai, Maharashtra, India.
Divya M RadhakrishnanDepartment of Neurology, All India Institute of Medical Sciences, New Delhi, India.
All India Institute of Medical Sciences · INBombay Hospital · INLokmanya Tilak Municipal General Hospital and Lokmanya Tilak Municipal Medical College · INMedanta The Medicity · INYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: COVID-19 infection is associated with neurological manifestations, including various types of movement disorders (MD). A thorough review of individual patients with COVID-19-induced MD would help in better understanding the clinical profile and outcome of these patients and in prognostication. Objective: We conducted an individual patient-systematic review to study the clinical and imaging profile and outcomes of patients with COVID-19-associated MD. Methods: A systematic literature search of PubMed, EMBASE, and Cochrane databases was conducted by two independent reviewers. Individual patient data COVID from case reports and case series on COVID-19-associated MD, published between December 2019 and December 2022, were extracted and analyzed. Results: Data of 133 patients with COVID-19-associated MD from 82 studies were analyzed. Mean age was 55 ± 18 years and 77% were males. A mixed movement disorder was most commonly seen (41%); myoclonus-ataxia was the most frequent (44.4%). Myoclonus significantly correlated with age (odds ratio (OR) 1.02 Conclusion: Myoclonus-ataxia was the most common movement disorder after COVID-19 infection. Myoclonus was seen in older individuals and usually improved. Tremor and parkinsonism developed after a long latency and did not improve in the short-term.

Indexed as

COVID-19de novo movement disordersmyoclonus-ataxiasystematic review

Identifiers

PMID38022478
PMCPMC10666879
OpenAlexW4387905582

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LicenceCC BY-NC-SA
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.