Evidence map›Paper›PMID 38021897›Full record

ReviewCureus2023

Impact of Silymarin Supplements on Liver Enzyme Levels: A Systematic Review.

Ernesto Calderon Martinez, Domenica Herrera, Saruveish Mogan, Zainab Hameed, Ayesha Altaf Jangda, Tayyaba J Khan, Palvi Mroke, Samar Sajid, Yash R Shah, Imran Baig

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

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  6. [Mechanisms of the Anti-Fibrotic Effect of Ginsenoside RhSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 7 countries.

Ernesto Calderon MartinezBiomedical Informatics, Universidad Nacional Autónoma de México, Mexico City, MEX.
Domenica HerreraInternal Medicine, Pontificia Universidad Católica del Ecuador, Quito, ECU.
Saruveish MoganFaculty of Medicine and Health Sciences, Universiti Malaysia Sarawak (UNIMAS), Kuching, MYS.
Zainab HameedInternal Medicine, Shifa College of Medicine, Islamabad, PAK.
Ayesha Altaf JangdaInternal Medicine, Ziauddin University, Karachi, PAK.
Tayyaba J KhanMedicine, Liaquat University of Medical and Health Sciences, Jamshoro, PAK.
Palvi MrokeInternal Medicine, Caribbean Medical University School of Medicine, Willemstad, CUW.
Samar SajidMedicine, Dow University of Health Sciences, Karachi, PAK.
Yash R ShahMedicine, GMERS (Gujarat Medical Education and Research Society) Medical College and Civil Hospital, Sola, Ahmedabad, IND.
Imran BaigInternal Medicine, Houston Methodist Hospital, Houston, USA.
Gujarat Cancer Society · INMethodist Hospital · USUniversidad Nacional Autónoma de México · MXUniversity College of Islamabad · PKCaribbean Research and Management of Biodiversity Foundation · CWZiauddin University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Silymarin, extracted from milk thistle (

Indexed as

hepatologyherbal supplementsliver enzyme levelssylimarinsystematic review

Identifiers

PMID38021897
PMCPMC10667129
OpenAlexW4387938627

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.