Evidence map›Paper›PMID 38021823›Full record

ArticleCureus2023

Parasympathetic Dominance Decreases the Choroidal Blood Flow Velocity Measured Using Laser Speckle Flowgraphy.

Fuka Kuwahara, Yuki Hashimoto, Natsumi Toh, Sakurako Imabayashi, Ami Sakamoto, Kanon Shiraishi, Rena Igawa, Takeshi Yoshitomi

Open access · diamondAbstract read
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Fuka KuwaharaDepartment of Orthoptics, Fukuoka International University of Health and Welfare, Fukuoka, JPN.
Yuki HashimotoDepartment of Orthoptics, Fukuoka International University of Health and Welfare, Fukuoka, JPN.
Natsumi TohDepartment of Orthoptics, Fukuoka International University of Health and Welfare, Fukuoka, JPN.
Sakurako ImabayashiDepartment of Orthoptics, Fukuoka International University of Health and Welfare, Fukuoka, JPN.
Ami SakamotoDepartment of Orthoptics, Fukuoka International University of Health and Welfare, Fukuoka, JPN.
Kanon ShiraishiDepartment of Orthoptics, Fukuoka International University of Health and Welfare, Fukuoka, JPN.
Rena IgawaDepartment of Orthoptics, Fukuoka International University of Health and Welfare, Fukuoka, JPN.
Takeshi YoshitomiDepartment of Orthoptics, Fukuoka International University of Health and Welfare, Fukuoka, JPN.
Fukuoka International University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to examine the changes to choroidal blood flow velocity using laser speckle flowgraphy (LSFG) in healthy eyes after warm water immersion at 40°C.

methodsData regarding the right eyes of 23 healthy volunteers were included. The mean blur rate (MBR) of the macula, which represents the choroidal blood flow velocity, was evaluated using LSFG. Intraocular pressure (IOP), systolic blood pressure (SBP), diastolic blood pressure (DBP), mean blood pressure (MBP), ocular perfusion pressure (OPP), and MBR were assessed at baseline, immediately after immersion (0 minutes), and 10, 20, and 30 minutes later.

resultsAt 0 minutes, SBP, DBP, MBP, and OPP values were lower than those at baseline. The MBR significantly declined immediately after immersion to -6.0 ± 5.2%. However, there were no changes in these parameters after 10, 20, or 30 minutes. A significant positive correlation was observed between the MBR, SBP, DBP, MBP, and OPP values. In healthy individuals, the dominant parasympathetic activity induced by warm stimulation reduced the choroidal hemodynamic rate in the macula and decreased systemic circulatory dynamics, which normalized after 10 minutes.

conclusionsThese findings suggest that the dominant parasympathetic activity induced by warm water immersion at 40°C may lead to a reduction in the systemic circulation rate and choroidal blood flow rate in the macula. These findings may help prevent and treat various retinal choroidal diseases, in which sympathetic hyperactivity is involved in the pathogenesis of the disease.

Indexed as

choroidal circulation hemodynamicslaser speckle flowgraphymean blur rateparasympathetic activitywarm water immersion

Identifiers

PMID38021823
PMCPMC10640924
OpenAlexW4387605301

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.