Evidence map›Paper›PMID 38021689›Full record

ArticleCureus2023

Embolic Phenomena of Libman-Sacks Endocarditis and Antiphospholipid Syndrome.

Asher Gorantla, Michael Schaible, Shruthi S Sivakumar, Anandita Kishore, Wayne Andrew-Palmer, Selin Unal, Michael Ramirez, Varshitha Panduranga, Adam S Budzikowski

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Asher GorantlaCardiology, State University of New York (SUNY) Downstate HSC, Brooklyn, USA.
Michael SchaibleInternal Medicine, State University of New York Downstate Health Sciences University, Brooklyn, USA.
Shruthi S SivakumarNeurology, State University of New York Downstate Health Sciences University, Brooklyn, USA.
Anandita KishoreInternal Medicine, Sisters of Charity Hospital, Buffalo, USA.
Wayne Andrew-PalmerInternal Medicine, State University of New York Downstate Health Sciences University, Brooklyn, USA.
Selin UnalInternal Medicine, State University of New York Downstate Health Sciences University, Brooklyn, USA.
Michael RamirezInternal Medicine, State University of New York Downstate Health Sciences University, Brooklyn, USA.
Varshitha PandurangaInternal Medicine, State University of New York Downstate Health Sciences University, Brooklyn, USA.
Adam S BudzikowskiDivision of Cardiovascular Medicine - Electrophysiology section, State University of New York Downstate Health Sciences University, Brooklyn, USA.
State University of New York · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with systemic lupus erythematosus (SLE) and antiphospholipid antibody syndrome (APS) are at high risk of developing arterial or venous thromboembolism and a state of systemic hypercoagulability. Libman-Sacks endocarditis (LSE) is a type of non-bacterial endocarditis usually seen in patients with systemic lupus erythematosus and antiphospholipid antibody syndrome. These vegetations dislodge easily and can cause profound neurological and systemic complications in the form of emboli. We describe one such case of a young woman with known SLE who presented with an acute middle cerebral artery (MCA) stroke and was found to have APS with extensive mitral valve vegetation, indicating Libman-Sacks endocarditis on echocardiography. Recognizing the increasing frequency of both APS and LSE in patients with SLE and screening patients, especially the younger population with SLE, for APS is vital. Furthermore, in those patients presenting with embolic events, echocardiography plays a key role as it can help expedite the diagnosis of LSE. Our case report also reiterates that warfarin, when compared to direct oral anticoagulants (DOAC), is superior in decreasing future embolic events.

Indexed as

antiphospholipid antibodyembolic phenomena: ischemic strokelibman sacks endocarditis (lse)systemic lupus erythromatosus

Identifiers

PMID38021689
PMCPMC10640721
OpenAlexW4387617178

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.