Evidence map›Paper›PMID 38021570›Full record

ArticleCureus2023

Rare Loxoscelism-Associated IgG Coombs-Positive Hemolytic Anemia Treated Successfully With Systemic Corticosteroids.

Anas Alqam, Joud Zakhour, Wissam Karam, Gerson Maldonado, Pavan S Reddy

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Anas AlqamDepartment of Internal Medicine, University of Kansas School of Medicine-Wichita, Wichita, USA.
Joud ZakhourDepartment of Internal Medicine, University of Kansas School of Medicine-Wichita, Wichita, USA.
Wissam KaramDepartment of Internal Medicine, University of Kansas School of Medicine-Wichita, Wichita, USA.
Gerson MaldonadoDepartment of Internal Medicine, University of Kansas School of Medicine-Wichita, Wichita, USA.
Pavan S ReddyDepartment of Hematology and Oncology, University of Kansas School of Medicine-Wichita, Wichita, USA.
Cancer Center of Kansas · USUniversity of Kansas · USWichita Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Loxoscelism-associated hemolytic anemia is a rare but critical complication of brown recluse spider bites. It may lead to various systemic manifestations, including jaundice, dark urine, and anemia-related symptoms, in addition to general loxoscelism symptoms such as skin lesions, fever, myalgia, nausea, and vomiting. Prompt diagnosis is crucial and requires recognizing typical laboratory findings such as low hemoglobin, elevated lactate dehydrogenase, reduced haptoglobin levels, and possibly a positive direct antiglobulin test. There is no definitive guideline for the treatment of loxoscelism-associated hemolytic anemia. we report a case of a 32-year-old female who developed severe Coombs-positive autoimmune hemolytic anemia following a brown recluse spider bite, with an improvement in hemoglobin levels and hemolysis indices after the administration of systemic corticosteroids.

Indexed as

brown recluse spider bitecoombs positive hemolytic anemiaimmune hemolytic anemialoxoscelismwarm autoimmune hemolytic anemia

Identifiers

PMID38021570
PMCPMC10658755
OpenAlexW4387844805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.