Treatment of osteonecrosis of the femoral head with multiple drilling and bone marrow mesenchymal stem cells expanded

Maria C Canencio Salgado, Omar Amado Pico, Claudia L Sossa, Martha Ligia Arango-Rodríguez

Abstract readCase Reports

In one paragraph

Article in American journal of stem cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Mesenchymal Stem Cell Therapy for Bone Repair of Human Hip Osteonecrosis with Bilateral Match-Control Evaluation: Impact of Tissue Source, Cell Count, Disease Stage, and Volume Size on 908 Hips.Cells · 2024
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Maria C Canencio SalgadoFacultad de Ciencias de la Salud, Universidad Autónoma de Bucaramanga - UNAB Bucaramanga 681003, Colombia.

Omar Amado PicoFacultad de Ciencias de la Salud, Universidad Autónoma de Bucaramanga - UNAB Bucaramanga 681003, Colombia.

Claudia L SossaFacultad de Ciencias de la Salud, Universidad Autónoma de Bucaramanga - UNAB Bucaramanga 681003, Colombia.

Martha Ligia Arango-RodríguezFacultad de Ciencias de la Salud, Universidad Autónoma de Bucaramanga - UNAB Bucaramanga 681003, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteonecrosis of the femoral head (ONFH) is a debilitating condition that predominantly affects young individuals, resulting in disability and involving significant healthcare costs. Therefore, it is crucial to develop an effective therapeutic strategy to treat this debilitating disease. In this context, autologous bone marrow-derived mesenchymal stem cells (auto-BM-MSCs) have emerged as a promising approach for treating ONFH. In this case report, we applied this therapy to a patient with ONFH and evaluated both its safety and therapeutic benefits. The treatment consisted of the administration of a single dose of 4×10

Indexed as

femoral headmesenchymal stem cells and platelet-rich plasmaOsteonecrosis

Identifiers

PMID38021456

PMCPMC10658132

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.