Evidence map›Paper›PMID 38021446›Full record

ReviewOncoTargets and therapy2023

Optimizing the Continuum of Care in Gastric Cancer.

Beatrice Riccò, Giulio Martinelli, Camilla Bardasi, Massimo Dominici, Andrea Spallanzani, Massimiliano Salati

Abstract readReview
In one paragraph

Review in OncoTargets and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Beatrice Riccò *Department of Oncology and Hematology, University Hospital of Modena, Modena, Italy.
Giulio Martinelli *Department of Oncology and Hematology, University Hospital of Modena, Modena, Italy.
Camilla BardasiDepartment of Oncology and Hematology, University Hospital of Modena, Modena, Italy.
Massimo DominiciDepartment of Oncology and Hematology, University Hospital of Modena, Modena, Italy.ORCID 0000-0002-4007-1503
Andrea SpallanzaniDepartment of Oncology and Hematology, University Hospital of Modena, Modena, Italy.ORCID 0000-0001-6955-7139
Massimiliano SalatiDepartment of Oncology and Hematology, University Hospital of Modena, Modena, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer (GC) still ranks as the fifth most common malignancy and the fourth leading cause of cancer-related death worldwide. Despite the recent progress in the therapeutic algorithm of the advanced disease with the advent of immune checkpoint inhibitors (ICIs) and next-generation HER2-directed therapies, survival rates remain poor, with a median survival hardly exceeding 12 months. Furthermore, only 40% of patients remain eligible for second- and later-line treatments due to the aggressiveness of the disease and the rapid deterioration of performance status (PS). Thus, current research is focusing either on the identification of novel treatment options or the development of personalized strategies to optimize the continuum of care and ultimately improve patients' outcome. In this article, we provide an overview of the current treatment landscape for advanced GC with a particular emphasis on later-line treatments and outline novel perspectives on the horizon.

Indexed as

continuum of caregastric cancergastroesophageal cancertarget therapies

Identifiers

PMID38021446
PMCPMC10680466

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.