Evidence map›Paper›PMID 38021405›Full record

ArticleF1000Research2023

parazitCUB: An R package to streamline the process of investigating the adaptations of parasites' codon usage bias.

Ali Mostafa Anwar, Salma Bayoumi, Sagy Elzalabany, Sameh Magdeldin, Amr E Ahmed

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Article in F1000Research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Ali Mostafa AnwarBiotechnology and Life Sciences Department, Faculty of Postgraduate Studies for Advanced Sciences, Beni-Suef University, Beni-Suef, Egypt.ORCID 0000-0002-5201-387X
Salma BayoumiBiochemistry Department, Faculty of Science, Alexandria University, Alexandria, Alexandria Governorate, Egypt.
Sagy ElzalabanyBiomedical Equipment Department, Badr University in Cairo, Badr City, Cairo Governorate, Egypt.
Sameh MagdeldinDepartment of Physiology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, Ismailia Governorate, Egypt.
Amr E AhmedBiotechnology and Life Sciences Department, Faculty of Postgraduate Studies for Advanced Sciences, Beni-Suef University, Beni-Suef, Egypt.ORCID 0000-0003-0628-4422

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Examining the intricate association between parasites and their hosts, particularly at the codon level, assumes paramount importance in comprehending evolutionary processes and forecasting the characteristics of novel parasites. While diverse metrics and statistical analyses are available to explore codon usage bias (CUB), there presently exists no dedicated tool for examining the co-adaptation of codon usage between parasites and hosts. Therefore, we introduce the parazitCUB R package to address this challenge in a scalable and efficient manner, as it is capable of handling extensive datasets and simultaneously analyzing of multiple parasites with optimized performance. parazitCUB enables the elucidation of parasite-host interactions and the evolutionary patterns of parasites through the implementation of various indices, cluster analysis, multivariate analysis, and data visualization techniques. The tool can be accessed at the following location: https://github.com/AliYoussef96/parazitCUB.

Indexed as

Codon UsageParasitesAnimalsBiological EvolutionCodonHost-Parasite InteractionsCodonAdaptationCodon Usage BiasMolecular evolutionNatural selectionparasitesRRStudio

Identifiers

PMID38021405
PMCPMC10682597

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