Evidence map›Paper›PMID 38021354›Full record

ArticleTranslational gastroenterology and hepatology2023

A fucoidan plant drink reduces

Qing-Liang Teng, Shu-Jing Sui, Zhen Zhu, Qing Gao, Hui Ge, Ke-Qiang Wang, Leonardo S Lino-Silva, Michael Sigal, Jonathan R White, Qi-Hui Peng and 1 more

Abstract read
In one paragraph

Article in Translational gastroenterology and hepatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Qing-Liang TengDepartment of Hematology, the Affiliated Hospital of Qingdao University Taian City Central Hospital, Taian, China.
Shu-Jing SuiDepartment of Gastroenterology, the Affiliated Hospital of Qingdao University Taian City Central Hospital, Taian, China.
Zhen ZhuDepartment of Pathology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Qing GaoDepartment of Emergency, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Hui GeDepartment of Gastroenterology, Shandong Provincial Taishan Hospital, Taian, China.
Ke-Qiang WangDongying Kanghui Health Center, Dongying, China.
Leonardo S Lino-SilvaDepartment of Surgical Pathology, Oncology Center Tula's General Hospital, Tula de Allende, Hidalgo, Mexico.
Michael SigalDepartment of Hepatology & Gastroenterology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Jonathan R WhiteNIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and the University of Nottingham, Nottingham, UK.
Qi-Hui PengBlue Regale Clinical Nutrition Technology Co., Ltd., Kunshan, China.
You-Zhen WeiResearch Center for Translational Medicine, the Affiliated Hospital of Qingdao University Taian City Central Hospital, Taian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: This multi-center, clinical study was conducted between October 2020 and July 2021. Hp infection was confirmed by urea breath test (UBT). A total of 122 patients with confirmed Hp infection were enrolled; after exclusion of incomplete data, 85 eligible patients (37 males and 48 females aged 20-81 years) were included in the final analysis. FPD (50 mL per vial) was orally administered twice daily for a 4-week cycle, and 41 patients completed an 8-week cycle. Results: No adverse event (AE) was reported in all 122 participants who had consumed FPD. The Hp eradication rate and clearance rate were 77.6% (66/85) and 20.0% (17/85), respectively, after 4 weeks of FPD consumption and 80.5% (33/41) and 26.8 (11/41) , respectively, after 8 weeks of consumption. Conclusions: The 4- and 8-week protocols of FPD consumption were safe and effective at reducing Hp load on the gastric mucosa, with Hp eradicated in the majority of participants.

Indexed as

eradicationfucoidanHelicobacter pylori (Hp)real worldtreatment

Identifiers

PMID38021354
PMCPMC10643181

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.