Evidence map›Paper›PMID 38021123›Full record

ArticleBiomedical optics express2023

Multimodal imaging of metabolic activities for distinguishing subtypes of breast cancer.

Zhi Li, Chloe Nguyen, Hongje Jang, David Hoang, SoeSu Min, Ellen Ackerstaff, Jason A Koutcher, Lingyan Shi

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Multimodal Optical Imaging Platform for Studying Cellular Metabolism.Journal of visualized experiments : JoVE · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Zhi LiDepartment of Bioengineering, University of California San Diego, California, USA.
Chloe NguyenDepartment of Bioengineering, University of California San Diego, California, USA.
Hongje JangDepartment of Bioengineering, University of California San Diego, California, USA.
David HoangDepartment of Bioengineering, University of California San Diego, California, USA.
SoeSu MinDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, USA.
Ellen AckerstaffDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, USA.
Jason A KoutcherDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, USA.
Lingyan ShiDepartment of Bioengineering, University of California San Diego, California, USA.ORCID https://orcid.org/0000-0003-1373-3206
University of California San Diego · USMemorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Elisa de Stanchina · 1985 to 2026
$347.4M
Training and Career Development CoreU54CA132378 · NCI · CITY COLLEGE OF NEW YORK · PI Bao Q Vuong · 2008 to 2026
$28.9M
The Human Lung BioMolecular Multi-Scale Atlas Program (HuBMAP-Lung)U54HL165443 · NHLBI · UNIVERSITY OF ROCHESTER · PI PRYHUBER, GLORIA S · 2022 to 2025
$8.0M
Kidney single cell and spatial molecular atlas project - KIDSSMAPU54DK134301 · NIDDK · WASHINGTON UNIVERSITY · PI JAIN, SANJAY · 2022 to 2025
$7.8M
High-resolution High-speed Photoacoustic and Ultrasound Imaging of SmallVessel Functions in Ischemic StrokeR01NS111039 · NINDS · DUKE UNIVERSITY · PI YAO, JUNJIE · 2019 to 2023
$2.7M
Sugar Probed SRS Volumetric imaging of Metabolic ActivitiesR01GM149976 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Lingyan Shi · 2023 to 2026
$1.6M
Novel Optical Imaging Approach to Study Neurovascular Coupling SystemR21NS125395 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SHI, LINGYAN · 2022 to 2022
$435k
NCI NIH HHS P30 CA008748NCI NIH HHS U54 CA132378NHLBI NIH HHS U54 HL165443NIDDK NIH HHS U54 DK134301NIGMS NIH HHS R01 GM149976NINDS NIH HHS R01 NS111039NINDS NIH HHS R21 NS125395
6 · The paper itself

Abstract

Triple negative breast cancer (TNBC) is a highly aggressive form of cancer. Detecting TNBC early is crucial for improving disease prognosis and optimizing treatment. Unfortunately, conventional imaging techniques fall short in providing a comprehensive differentiation of TNBC subtypes due to their limited sensitivity and inability to capture subcellular details. In this study, we present a multimodal imaging platform that integrates heavy water (D

Identifiers

PMID38021123
PMCPMC10659775
OpenAlexW4387132428

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.