Evidence map›Paper›PMID 38021111›Full record

ArticleBiomedical optics express2023

Automated pipeline for breast cancer diagnosis using US assisted diffuse optical tomography.

Minghao Xue, Menghao Zhang, Shuying Li, Yun Zou, Quing Zhu

Abstract read
In one paragraph

Article in Biomedical optics express, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Convolutional-transformer fusion of ultrasound and diffuse optical tomography for breast lesion classification.Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Minghao XueDepartment of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO 63130, USA.
Menghao ZhangDepartment of Electrical & Systems Engineering, Washington University in St. Louis, St. Louis, MO 63130, USA.
Shuying LiDepartment of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO 63130, USA.
Yun ZouDepartment of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO 63130, USA.
Quing ZhuDepartment of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO 63130, USA.ORCID https://orcid.org/0000-0002-1837-2588

Funding

Improving diagnostic US for reduction of benign breast biopsies using US-guided Optical TomographyR01CA228047 · NCI · WASHINGTON UNIVERSITY · PI POPLACK, STEVEN, ZHU, QUING · 2019 to 2023
$1.9M
NCI NIH HHS R01 CA228047
6 · The paper itself

Abstract

Ultrasound (US)-guided diffuse optical tomography (DOT) is a portable and non-invasive imaging modality for breast cancer diagnosis and treatment response monitoring. However, DOT data pre-processing and imaging reconstruction often require labor intensive manual processing which hampers real-time diagnosis. In this study, we aim at providing an automated US-assisted DOT pre-processing, imaging and diagnosis pipeline to achieve near real-time diagnosis. We have developed an automated DOT pre-processing method including motion detection, mismatch classification using deep-learning approach, and outlier removal. US-lesion information needed for DOT reconstruction was extracted by a semi-automated lesion segmentation approach combined with a US reading algorithm. A deep learning model was used to evaluate the quality of the reconstructed DOT images and a two-step deep-learning model developed earlier is implemented to provide final diagnosis based on US imaging features and DOT measurements and imaging results. The presented US-assisted DOT pipeline accurately processed the DOT measurements and reconstruction and reduced the procedure time to 2 to 3 minutes while maintained a comparable classification result with manually processed dataset.

Identifiers

PMID38021111
PMCPMC10659805

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.