Evidence map›Paper›PMID 38020916›Full record

ReviewFrontiers in cell and developmental biology2023

Not all (cells) who wander are lost: Upstream migration as a pervasive mode of amoeboid cell motility.

Alexander Buffone, Daniel A Hammer, Sarah Hyun Ji Kim, Nicholas R Anderson, Ai Mochida, Dong-Hun Lee, Subham Guin

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. INTEGRIN FUNCTION IN LEUKOCYTE-MEDIATED INFLAMMATION-ACTINOPATHIES IN IMMUNE DISEASES.Transactions of the American Clinical and Climatological Association · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Alexander BuffoneDepartment of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ, United States.
Daniel A HammerDepartment of Bioengineering, University of Pennsylvania, Philadelphia, PA, United States.
Sarah Hyun Ji KimDepartment of Medicine, University of California San Diego, La Jolla, CA, United States.
Nicholas R AndersonCarisma Therapeutics, Philadelphia, PA, United States.
Ai MochidaDepartment of Bioengineering, University of Pennsylvania, Philadelphia, PA, United States.
Dong-Hun LeeDepartment of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, PA, United States.
Subham GuinDepartment of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ, United States.
University of Pennsylvania · USNew Jersey Institute of Technology · USCarisma Therapeutics (United States) · USUniversity of California San Diego · US

Funding

Controlling the upstream migration of neutrophils by manipulating the function of Mac-1 and LFA-1R01GM143357 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI HAMMER, DANIEL A · 2022 to 2025
$1.2M
NIGMS NIH HHS R01 GM143357
6 · The paper itself

Abstract

Leukocytes possess the ability to migrate upstream-against the direction of flow-on surfaces of specific chemistry. Upstream migration was first characterized

Indexed as

hematopoietic stem cellsICAM-1inflammationleukocytesLFA-1migrationT-cells

Identifiers

PMID38020916
PMCPMC10651737
OpenAlexW4388225542

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.