ArticleFrontiers in cell and developmental biology2023
Ethical, legal and social aspects of human cerebral organoids and their governance in Germany, the United Kingdom and the United States.
Article in Frontiers in cell and developmental biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- From consent to participatory governance: The need for multi-stakeholder alignment in iPSC-based drug repurposing.Stem cell reports · 2026Article
- Towards learning and memory risk assessment with human brain organoids: barriers and opportunities.Frontiers in toxicology · 2026Review
- What's Economics Got to Do with It? Providing Theoretical Clarity on ELSA of AI.Science and engineering ethics · 2025Article
- The ethical aspects of human organ-on-chip models: A mapping review.Stem cell reports · 2025Review
- Charting bioethical frontiers: China's human organoid guidelines in a global context.Military Medical Research · 2025Article
- Bioengineering ethics for the age of microphysiological systems.Frontiers in bioengineering and biotechnology · 2025Article
- Neuroethics and AI ethics: a proposal for collaboration.BMC neuroscience · 2024Review
- Cardiac organoids do not warrant additional moral scrutiny.BMC medical ethics · 2024Article
- Brain organoids and organoid intelligence from ethical, legal, and social points of view.Frontiers in artificial intelligence · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
23 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human cerebral organoids (HCOs) are model systems that enable researchers to investigate the human brain in ways that had previously been impossible. The emergence of HCOs was accompanied by both expert and layperson discussions concerning the possibility of these novel entities developing sentience or consciousness. Such concerns are reflected in deliberations about how to handle and regulate their use. This perspective article resulted from an international and interdisciplinary research retreat "Ethical, Legal and Social Aspects of Human Cerebral Organoids and their Governance in Germany, the United Kingdom and the United States", which took place in Tübingen, Germany, in August 2022. The retreat focused on whether HCO research requires new ethical and regulatory approaches. It addressed epistemic issues around the detection and theorisation of consciousness, ethical concerns around moral status and research conduct, difficulties for legislation and guidelines managing these entities, and public engagement.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.