Evidence map›Paper›PMID 38020869›Full record

ArticleEvolutionary applications2023

From maternal glucocorticoid and thyroid hormones to epigenetic regulation of offspring gene expression: An experimental study in a wild bird species.

Mikaela Hukkanen, Bin-Yan Hsu, Nina Cossin-Sevrin, Mélanie Crombecque, Axelle Delaunay, Lotta Hollmen, Riina Kaukonen, Mikko Konki, Riikka Lund, Coline Marciau and 2 more

Open access · goldAbstract read
In one paragraph

Article in Evolutionary applications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Mikaela HukkanenInstitute for Molecular Medicine Finland University of Helsinki Helsinki Finland.ORCID https://orcid.org/0000-0002-8574-8274
Bin-Yan HsuDepartment of Biology University of Turku Turku Finland.
Nina Cossin-SevrinDepartment of Biology University of Turku Turku Finland.
Mélanie CrombecqueDepartment of Biology University of Turku Turku Finland.
Axelle DelaunayInstitut des Sciences de l'Evolution de Montpellier (ISEM) Université de Montpellier, CNRS, IRD, EPHE Montpellier France.
Lotta HollmenDepartment of Biology University of Turku Turku Finland.
Riina KaukonenTurku Bioscience Centre University of Turku and Åbo Akademi University Turku Finland.
Mikko KonkiTurku Bioscience Centre University of Turku and Åbo Akademi University Turku Finland.
Riikka LundTurku Bioscience Centre University of Turku and Åbo Akademi University Turku Finland.
Coline MarciauDepartment of Biology University of Turku Turku Finland.
Antoine StierDepartment of Biology University of Turku Turku Finland.
Suvi RuuskanenDepartment of Biology University of Turku Turku Finland.
University of Turku · FIÅbo Akademi University · FICentre National de la Recherche Scientifique · FRUniversity of Helsinki · FIUniversity of Tasmania · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Offspring phenotype at birth is determined by its genotype and the prenatal environment including exposure to maternal hormones. Variation in both maternal glucocorticoids and thyroid hormones can affect offspring phenotype, but the underlying molecular mechanisms, especially those contributing to long-lasting effects, remain unclear. Epigenetic changes (such as DNA methylation) have been postulated as mediators of long-lasting effects of early-life environment. In this study, we determined the effects of elevated prenatal glucocorticoid and thyroid hormones on handling stress response (breath rate) as well as DNA methylation and gene expression of glucocorticoid receptor (GR) and thyroid hormone receptor (THR) in great tits (

Indexed as

epigeneticshormonematernal effectsmethylationParus majorprenatal

Identifiers

PMID38020869
PMCPMC10660793
OpenAlexW4387340482

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.