Evidence map›Paper›PMID 38020587›Full record

ArticleFrontiers in neurology2023

Validation of the Body Scan

Jean-Pierre Riveline, Roberto Mallone, Clarisse Tiercelin, Fetta Yaker, Laure Alexandre-Heymann, Lysa Khelifaoui, Florence Travert, Claire Fertichon, Jean-Baptiste Julla, Tiphaine Vidal-Trecan and 4 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05178459 (Withings Study to Analyse the Accuracy of Screening Small Fiver Neuropathy With a Bathroom Scale), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05178459 completednot on this map

Withings Study to Analyse the Accuracy of Screening Small Fiver Neuropathy With a Bathroom Scale

TypeobservationalSponsorWithingsRan2022 to 2022Enrolled177ConditionsNeuropathyArmsNeuropathy measurement
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Jean-Pierre RivelineDiabetology and Endocrinology Department, Lariboisière Hospital, Paris, France.
Roberto MalloneDiabetology Department, Cochin Hospital, Paris, France.
Clarisse TiercelinDiabetology Department, Cochin Hospital, Paris, France.
Fetta YakerDiabetology Department, Cochin Hospital, Paris, France.
Laure Alexandre-HeymannDiabetology Department, Cochin Hospital, Paris, France.
Lysa KhelifaouiDiabetology - Endocrinology and Nutrition Department, Bichat-Claude-Bernard Hospital, Paris, France.
Florence TravertDiabetology - Endocrinology and Nutrition Department, Bichat-Claude-Bernard Hospital, Paris, France.
Claire FertichonDiabetology - Endocrinology and Nutrition Department, Bichat-Claude-Bernard Hospital, Paris, France.
Jean-Baptiste JullaDiabetology and Endocrinology Department, Lariboisière Hospital, Paris, France.
Tiphaine Vidal-TrecanDiabetology and Endocrinology Department, Lariboisière Hospital, Paris, France.
Louis PotierDiabetology - Endocrinology and Nutrition Department, Bichat-Claude-Bernard Hospital, Paris, France.
Jean-Francois GautierDiabetology and Endocrinology Department, Lariboisière Hospital, Paris, France.
Etienne LargerDiabetology Department, Cochin Hospital, Paris, France.
Jean-Pascal LefaucheurUnité de Neurophysiologie Clinique, Hôpital Henri Mondor, AP-HP, Créteil, France.
Hôpital Cochin · FRHôpital Bichat-Claude-Bernard · FRHôpital Lariboisière · FRUniversité Paris-Est Créteil · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Sudomotor dysfunction is one of the earliest manifestations of small fiber neuropathy (SFN), reflecting the alteration of sympathetic C fiber innervation of the sweat glands. Among other techniques, such innervation can be assessed by measuring electrochemical skin conductance (ESC) in microsiemens (μS). In this study, ESC was measured at the feet to detect distal SFN. For this objective, the performance of a new device, the Body Scan Methods: In patients with diabetes with or without neuropathy or non-diabetic patients with lower-limb neuropathy, the diagnostic performance of the Body Scan Results: A total of 147 patients (52% men, mean age 59 years old, 76% diabetic) were included in the analysis. The sensitivity and specificity to detect at least moderate or severe SFN were: Se70 = 0.91 ([0.83, 0.96]), Sp70 = 0.97 ([0.88, 0.99]), Se50 = 0.91 ([0.80, 0.98]), and Sp50 = 0.99 ([0.94, 1]), respectively. The bias and 95% limits of agreement were 1.5 [-5.4, 8.4]. The MAE was 2.9 and the RMSE 3.8. The intra-sample variability was 2.0 for the Body Scan Conclusion: The ESC measurements provided by the Body Scan Clinical trial registration: ClinicalTrials.gov, identifier NCT05178459.

Indexed as

amyloidosisautonomic testingdiabetesdiagnosissmall fiber neuropathysudomotor functionsympathetic nerve fibers

Identifiers

PMID38020587
PMCPMC10644320
OpenAlexW4388078301

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.