Evidence map›Paper›PMID 38020140›Full record

ArticleFrontiers in medicine2023

Prolonged survival of a patient with active MDR-TB HIV co-morbidity: insights from a

Mor Rubinstein, Andrei Makhon, Yelena Losev, Gal Zizelski Valenci, Yair E Gatt, Hanah Margalit, Ephraim Fass, Ina Kutikov, Omer Murik, David A Zeevi and 6 more

Abstract read
In one paragraph

Article in Frontiers in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Mor Rubinstein *National Public Health Laboratory, Public Health Directorate, Ministry of Health, Tel Aviv, Israel.
Andrei Makhon *National Public Health Laboratory, Public Health Directorate, Ministry of Health, Tel Aviv, Israel.
Yelena LosevNational Public Health Laboratory, Public Health Directorate, Ministry of Health, Tel Aviv, Israel.
Gal Zizelski ValenciNational Public Health Laboratory, Public Health Directorate, Ministry of Health, Tel Aviv, Israel.
Yair E GattDepartment of Microbiology and Molecular Genetics, Institute for Medical Research Israel-Canada, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.
Hanah MargalitDepartment of Microbiology and Molecular Genetics, Institute for Medical Research Israel-Canada, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.
Ephraim FassNational Public Health Laboratory, Public Health Directorate, Ministry of Health, Tel Aviv, Israel.
Ina KutikovNational Public Health Laboratory, Public Health Directorate, Ministry of Health, Tel Aviv, Israel.
Omer MurikTranslational Genomics Laboratory, Medical Genetics Institute, Shaare Zedek Medical Center, Jerusalem, Israel.
David A ZeeviTranslational Genomics Laboratory, Medical Genetics Institute, Shaare Zedek Medical Center, Jerusalem, Israel.
Michal SavyonTel Aviv District Health Office, Ministry of Health, Tel Aviv, Israel.
Luba TauTel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Hasia Kaidar ShwartzNational Public Health Laboratory, Public Health Directorate, Ministry of Health, Tel Aviv, Israel.
Zeev DveyrinNational Public Health Laboratory, Public Health Directorate, Ministry of Health, Tel Aviv, Israel.
Efrat RormanNational Public Health Laboratory, Public Health Directorate, Ministry of Health, Tel Aviv, Israel.
Israel NissanNational Public Health Laboratory, Public Health Directorate, Ministry of Health, Tel Aviv, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coinfection of HIV and multidrug-resistant tuberculosis (MDR-TB) presents significant challenges in terms of the treatment and prognosis of tuberculosis, leading to complexities in managing the disease and impacting the overall outcome for TB patients. This study presents a remarkable case of a patient with MDR-TB and HIV coinfection who survived for over 8 years, despite poor treatment adherence and comorbidities. Whole genome sequencing (WGS) of the infecting

Indexed as

acquired immunodeficiency syndrome (AIDS)dormancyHspXhuman immunodeficiency virus (HIV)in vivo evolutionmultidrug-resistant tuberculosis (MDR-TB)Mycobacterium tuberculosis (MTB)whole genome sequencing (WGS)

Identifiers

PMID38020140
PMCPMC10657812

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.