Evidence map›Paper›PMID 38020041›Full record

ArticleRSC advances2023

Development of a cationic polyethyleneimine-poly(lactic-

Shannon R Tracey, Peter Smyth, Una M Herron, James F Burrows, Andrew J Porter, Caroline J Barelle, Christopher J Scott

Abstract read
In one paragraph

Article in RSC advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Emerging Cationic Nanovaccines.Pharmaceutics · 2024
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shannon R TraceyQueen's University Belfast, The Patrick G Johnston Centre for Cancer Research 97 Lisburn Road Belfast Northern Ireland BT9 7AE UK.
Peter SmythQueen's University Belfast, The Patrick G Johnston Centre for Cancer Research 97 Lisburn Road Belfast Northern Ireland BT9 7AE UK.
Una M HerronQueen's University Belfast, The Patrick G Johnston Centre for Cancer Research 97 Lisburn Road Belfast Northern Ireland BT9 7AE UK.
James F BurrowsQueen's University Belfast, School of Pharmacy Belfast BT9 7BL UK.ORCID https://orcid.org/0000-0002-9677-200X
Andrew J PorterElasmogen Aberdeen UK.
Caroline J BarelleElasmogen Aberdeen UK.
Christopher J ScottQueen's University Belfast, The Patrick G Johnston Centre for Cancer Research 97 Lisburn Road Belfast Northern Ireland BT9 7AE UK.ORCID https://orcid.org/0000-0002-7582-3808

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intracellular delivery of proteins, peptides and biologics is an emerging field which has the potential to provide novel opportunities to target intracellular proteins, previously deemed 'undruggable'. However, the delivery of proteins intracellularly remains a challenge. Here, we present a cationic nanoparticle delivery system for enhanced cellular delivery of proteins through use of a polyethyleneimine and poly-(lactic-

Identifiers

PMID38020041
PMCPMC10654694

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.