Evidence map›Paper›PMID 38020008›Full record

ReviewRSC advances2023

Evolving approaches in glioma treatment: harnessing the potential of copper metabolism modulation.

Riccardo Cazzoli, Agata Zamborlin, Maria Laura Ermini, Antonietta Salerno, Manuela Curcio, Fiore Pasquale Nicoletta, Francesca Iemma, Orazio Vittorio, Valerio Voliani, Giuseppe Cirillo

Abstract readReview
In one paragraph

Review in RSC advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Riccardo CazzoliChildren's Cancer Institute Australia, Lowy Cancer Research Centre, University of New South Wales Sydney NSW Australia.
Agata ZamborlinNEST-Scuola Normale Superiore Piazza San Silvestro 12 - 56127 Pisa Italy.
Maria Laura ErminiCenter for Nanotechnology Innovation, Istituto Italiano di Tecnologia Piazza San Silvestro 12 - 56127 Pisa Italy.
Antonietta SalernoChildren's Cancer Institute Australia, Lowy Cancer Research Centre, University of New South Wales Sydney NSW Australia.
Manuela CurcioDepartment of Pharmacy Health and Nutritional Science, University of Calabria 87036 Rende Italy giuseppe.cirillo@unical.it +39 0984493208.
Fiore Pasquale NicolettaDepartment of Pharmacy Health and Nutritional Science, University of Calabria 87036 Rende Italy giuseppe.cirillo@unical.it +39 0984493208.
Francesca IemmaDepartment of Pharmacy Health and Nutritional Science, University of Calabria 87036 Rende Italy giuseppe.cirillo@unical.it +39 0984493208.
Orazio VittorioChildren's Cancer Institute Australia, Lowy Cancer Research Centre, University of New South Wales Sydney NSW Australia.
Valerio VolianiCenter for Nanotechnology Innovation, Istituto Italiano di Tecnologia Piazza San Silvestro 12 - 56127 Pisa Italy.ORCID https://orcid.org/0000-0003-1311-3349
Giuseppe CirilloDepartment of Pharmacy Health and Nutritional Science, University of Calabria 87036 Rende Italy giuseppe.cirillo@unical.it +39 0984493208.ORCID https://orcid.org/0000-0002-9592-1333

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The key properties and high versatility of metal nanoparticles have shed new perspectives on cancer therapy, with copper nanoparticles gaining great interest because of the ability to couple the intrinsic properties of metal nanoparticles with the biological activities of copper ions in cancer cells. Copper, indeed, is a cofactor involved in different metabolic pathways of many physiological and pathological processes. Literature data report on the use of copper in preclinical protocols for cancer treatment based on chemo-, photothermal-, or copper chelating-therapies. Copper nanoparticles exhibit anticancer activity

Identifiers

PMID38020008
PMCPMC10661684

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.