Evidence map›Paper›PMID 38019907›Full record

ArticleScience advances2023

Lipid-anchored proteasomes control membrane protein homeostasis.

Ruizhu Zhang, Shuxian Pan, Suya Zheng, Qingqing Liao, Zhaodi Jiang, Dixian Wang, Xuemei Li, Ao Hu, Xinran Li, Yezhang Zhu and 13 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Cellular and systemic modifiers of alpha-synuclein proteostasis.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors at 7 institutions in 3 countries.

Ruizhu ZhangZhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou 310058, China.ORCID 0009-0001-2444-8788
Shuxian PanZhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou 310058, China.ORCID 0009-0004-0175-8881
Suya ZhengZhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou 310058, China.
Qingqing LiaoZhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0002-6356-7704
Zhaodi JiangNational Institute of Biological Sciences, Beijing 102206, China.ORCID 0000-0001-9480-6942
Dixian WangDepartment of Human Anatomy, Histology and Embryology, System Medicine Research Center, and Department of Pathology of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China.ORCID 0000-0002-8065-9782
Xuemei LiZhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou 310058, China.
Ao HuHubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Taikang Center for Life and Medical Sciences, Taikang Medical School, Wuhan University, Wuhan 430072, China.ORCID 0000-0001-5763-204X
Xinran LiZhejiang University-Hangzhou Global Scientific and Technological Innovation Center, Hangzhou 311200, China.ORCID 0000-0003-2805-3510
Yezhang ZhuZhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0001-6310-9108
Xiaoqi ShenZhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou 310058, China.
Jing LeiDepartment of Neurobiology and Department of Neurology of Second Affiliated Hospital, NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University School of Medicine, Hangzhou 310058, China.ORCID 0000-0003-4331-4117
Siming ZhongZhejiang University-University of Edinburgh Institute, Zhejiang University, Haining 314400, China.ORCID 0009-0007-0135-6980
Xiaomei ZhangZhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0002-3231-929X
Lingyun HuangZhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou 310058, China.ORCID 0009-0004-3613-9829
Xiaorong WangDepartment of Physiology and Biophysics, University of California-Irvine, Irvine, CA 92697, USA.
Lan HuangDepartment of Physiology and Biophysics, University of California-Irvine, Irvine, CA 92697, USA.ORCID 0000-0002-3140-4687
Li ShenZhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0002-5696-2191
Bao-Liang SongHubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Taikang Center for Life and Medical Sciences, Taikang Medical School, Wuhan University, Wuhan 430072, China.ORCID 0000-0002-6397-5935
Jing-Wei ZhaoDepartment of Human Anatomy, Histology and Embryology, System Medicine Research Center, and Department of Pathology of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China.
Zhiping WangDepartment of Neurobiology and Department of Neurology of Second Affiliated Hospital, NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University School of Medicine, Hangzhou 310058, China.ORCID 0000-0001-8944-9557
Bing YangZhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0001-6739-2932
Xing GuoZhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0002-9794-1725
Zhejiang University · CNUniversity of California, Irvine · USSecond Affiliated Hospital of Zhejiang University · CNSir Run Run Shaw Hospital · CNWuhan University · CNNational Institute of Biological Sciences, Beijing · CNZhejiang University-University of Edinburgh Institute · CN

Funding

Proteomics of the Proteasome Interacting NetworksR01GM074830 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI HUANG, LAN · 2005 to 2022
$6.1M
Supplement: Advancing Proteomics Technologies to Decipher the Ubiquitin-Proteasome SystemR35GM145249 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI Lan Huang · 2022 to 2026
$3.2M
NIGMS NIH HHS R01 GM074830NIGMS NIH HHS R35 GM145249
6 · The paper itself

Abstract

Protein degradation in eukaryotic cells is mainly carried out by the 26

Indexed as

Membrane ProteinsProteasome Endopeptidase ComplexAnimalsEndoplasmic Reticulum-Associated DegradationHumansLipidsMiceMice, NudeProteostasisLipidsMembrane ProteinsProteasome Endopeptidase Complex

Identifiers

PMID38019907
PMCPMC10686573
OpenAlexW4389127897

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.