Evidence map›Paper›PMID 38019871›Full record

ArticlePloS one2023

The association between serum prolactin levels and live birth rates in non-PCOS patients: A retrospective cohort study.

Xiaoyuan Xu, Aimin Yang, Yan Han, Wei Wang, Guimin Hao, Na Cui

Abstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaoyuan XuDepartment of Reproductive Medicine, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Aimin YangDepartment of Reproductive Medicine, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Yan HanDepartment of Reproductive Medicine, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Wei WangDepartment of Reproductive Medicine, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Guimin HaoDepartment of Reproductive Medicine, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Na CuiDepartment of Reproductive Medicine, The Second Hospital of Hebei Medical University, Shijiazhuang, China.ORCID 0000-0003-2535-9629

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesThis paper aimed to analyze the relationship between baseline prolactin (PRL) levels and live birth rates (LBRs) in patients undergoing embryo transfer who did not have polycystic ovarian syndrome (PCOS) using a retrospective design. Patient(s): A total of 20,877 patients who had undergone IVF/intracytoplasmic sperm injection (ICSI) between December 2014 and December 2019. MATERIALS AND

methodsWe examined the association between PRL concentrations and LBRs using multivariate regression analysis. In addition, a model for nonlinear relationships based on a two-part linear regression was developed.

resultsFollowing adjustment for confounding factors, multivariate regression analysis confirmed a statistically significant correlation between serum PRL and LBR. Particularly, when blood PRL content was less than 14.8 ng/mL, there exists a positive relation between serum PRL and LBRs. In contrast, once PRL concentrations surpassed the inflection point at 14.8 ng/mL, a meaningful relationship could no longer be inferred between serum PRL and LBR.

conclusionsBasal serum PRL levels were segmentally connected with LBRs.

Indexed as

Polycystic Ovary SyndromeBirth RateFemaleFertilization in VitroHumansLive BirthMalePregnancyPregnancy RateProlactinRetrospective StudiesSemenProlactin

Identifiers

PMID38019871
PMCPMC10686428

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