Evidence map›Paper›PMID 38019699›Full record

ArticleInfluenza and other respiratory viruses2023

Burden of seasonal influenza in the Swiss adult population during the 2016/2017-2018/2019 influenza seasons.

Daniel Ammann, Jana Bilger, Matthew M Loiacono, Susanne G Oberle, Andreas Dounas, Oriol Manuel, Mark Pletscher

Open access · goldAbstract read
In one paragraph

Article in Influenza and other respiratory viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Daniel AmmannBern University of Applied Sciences Bern Switzerland.ORCID 0009-0006-9117-6942
Jana BilgerBern University of Applied Sciences Bern Switzerland.
Matthew M LoiaconoGlobal Medical Evidence Generation Sanofi Vaccines Swiftwater Pennsylvania USA.ORCID 0000-0001-8100-465X
Susanne G OberleMedical Affairs Sanofi Vaccines Rotkreuz Switzerland.
Andreas DounasMedical Affairs Sanofi Vaccines Rotkreuz Switzerland.
Oriol ManuelInfectious Diseases Service and Transplantation Center Lausanne University Hospital and University of Lausanne Lausanne Switzerland.
Mark PletscherBern University of Applied Sciences Bern Switzerland.
Bern University of Applied Sciences · CHSanofi (Switzerland) · CHSanofi (United States) · USUniversity of Lausanne · CH

Funding

Sanofi
6 · The paper itself

Abstract

backgroundEvidence on the burden of seasonal influenza in Switzerland is scarce, yet it is critical for the design of effective prevention and control measures. The objective of this study was to assess influenza-related resource utilization, health care expenditures and quality-adjusted life-years (QALYs) lost in Switzerland across the 2016/2017-2018/2019 influenza seasons.

methodsWe retrospectively analyzed multiple real-world data sources to calculate epidemiological and health outcomes, QALYs lost, and direct medical costs due to influenza in the Swiss adult population. Subgroups included residents 18-49, 50-64, and 65+ years of age. The observation period was Week 26, 2016, to Week 25, 2019.

resultsAcross the three seasons, we estimated seasonal averages of 203,090 (se ± 26,717) general practitioner (GP) visits for influenza-like illness (ILI) 4944 (se ± 785) influenza-attributable hospitalizations and 1355 (se ± 169) excess deaths attributable to influenza. We estimated a total loss of 8429 (2016/2017), 11,179 (2017/2018), and 7701 (2018/2019) QALYs due to influenza. On average, 88% of the loss in QALYs was attributed to premature deaths due to influenza. The total direct medical costs amounted to 44.4 (2016/2017), 77.3 (2017/2018), and 64.5 (2018/2019) million euros. On average, 79.6% of the total costs arose due to hospitalizations.

conclusionsIn Switzerland, the burden of influenza on patients and payers is significant and particularly high in the elderly population. Policy interventions to increase vaccination rates and the uptake of more effective vaccines among the elderly are needed to reduce the burden of influenza.

Indexed as

Influenza, HumanInfluenza VaccinesAdultAgedHumansRetrospective StudiesSeasonsSwitzerlandInfluenza Vaccinesburden of diseaseepidemiologyhumaninfluenza

Identifiers

PMID38019699
PMCPMC10667819
OpenAlexW4388990631

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.