Evidence map›Paper›PMID 38019592›Full record

ArticleJournal of addiction medicine

Xylazine-associated Wounds: Clinical Experience From a Low-barrier Wound Care Clinic in Philadelphia.

Rachel McFadden, Sara Wallace-Keeshen, Kristi Petrillo Straub, Rebecca A Hosey, Rachel Neuschatz, Keara McNulty, Ashish P Thakrar

Open access · hybridAbstract read
In one paragraph

Article in Journal of addiction medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
15.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 52 citations in OpenAlex.

  1. Review
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  13. The Donovan Memorial Lecture: 'Fentanyl-Plus': A New Era of Fentanyl Polydrug Combinations in the North American Overdose Crisis.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2026
    Article
  14. Review
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  17. Destructive Xylazine Wounds: A New Entity Faced by Thoracic Surgeons.Annals of thoracic surgery short reports · 2025
    Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Rachel McFaddenFrom the Prevention Point Philadelphia, Philadelphia, PA (RMF, SW-K, KPS, RH, KMN); Center for Addiction Medicine and Policy (CAMP), University of Pennsylvania, Philadelphia, PA (RMF, APT); Stephen Klein Wellness Center, Project HOME, Philadelphia, PA (SW-K); Leonard A. Lauder Community Care Nurse Practitioner Program, University of Pennsylvania School of Nursing, Philadelphia, PA (RH); Division of Substance Use Prevention and Harm Reduction, Philadelphia Department of Public Health, Philadelphia, PA (RN); and Division of General Internal Medicine, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA (APT).
Sara Wallace-Keeshen
Kristi Petrillo Straub
Rebecca A Hosey
Rachel Neuschatz
Keara McNulty
Ashish P Thakrar
Aston Particle Technologies (United Kingdom) · GB

Funding

Advancing Clinical Research Training within Addiction Residency ProgramsR25DA033211 · NIDA · BOSTON MEDICAL CENTER · PI Patrick O'Connor, JEFFREY H. SAMET · 2012 to 2026
$4.2M
NIDA NIH HHS R25 DA033211
6 · The paper itself

Abstract

abstractThe veterinary sedative xylazine is spreading in unregulated opioid supplies across North America. Among people who use drugs with repeated exposure to xylazine, a distinct wound type has emerged. Here, we describe these wounds and share our experience treating them in a nurse-led, low-barrier wound care clinic in Philadelphia, PA. We propose a reimagining of wound treatment across settings to better serve people who use drugs, and we advocate for stronger protections against the harms of an increasingly adulterated drug supply. Our perspective from the epicenter of the xylazine crisis can inform the response of communities across the country who are starting to face harms associated with xylazine.

Indexed as

Hypnotics and SedativesXylazineAnalgesics, OpioidHumansPhiladelphiaAnalgesics, OpioidHypnotics and SedativesXylazine

Identifiers

PMID38019592
PMCPMC10967264
OpenAlexW4389132304

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.