Evidence map›Paper›PMID 38019336›Full record

ArticleMedical oncology (Northwood, London, England)2023

In vitro evaluation of p-coumaric acid and naringin combination in human epidermoid carcinoma cell line (A431).

Pradeep Velusamy, Sridhar Muthusami, Ramakrishnan Arumugam

Abstract read
PubMed Publisher
In one paragraph

Article in Medical oncology (Northwood, London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. LC-ESI-MS/MS Analysis ofMolecules (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Article
  4. An Updated Review Summarizing the Anticancer Potential of Naringenin.Endocrine, metabolic & immune disorders drug targets · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Pradeep VelusamyDepartment of Biochemistry, Karpagam Academy of Higher Education, Deemed to be University, Coimbatore, Tamil Nadu, 32, India.
Sridhar MuthusamiDepartment of Biochemistry, Karpagam Academy of Higher Education, Deemed to be University, Coimbatore, Tamil Nadu, 32, India.
Ramakrishnan ArumugamDepartment of Biochemistry, Karpagam Academy of Higher Education, Deemed to be University, Coimbatore, Tamil Nadu, 32, India. ramakrishnanA1991@gmail.com.ORCID http://orcid.org/0000-0001-8197-0014
Karpagam Academy of Higher Education · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is considered most detrimental due to high mortality worldwide. Among them, skin cancers play a major part by affecting one in three cancer patients globally. About 2-3 million cancer cases were reported to be non-melanoma and melanoma skin cancers, respectively. Although chemotherapeutic drugs act on cancer cells but results in long-lasting morbidities which affects one's quality of life and also works only in the initial stage of the cancer. Hence, an idea of traditional medicine to cure the disease efficiently with less side effects was pursued by the researchers. We have assessed the combination effect of p-coumaric acid and naringin in exerting anticancer activity using A431 (epidermoid carcinoma) cells. The MTT analysis of the combination on A431 cells showed the least IC

Indexed as

Carcinoma, Squamous CellSkin NeoplasmsCell LineCoumaric AcidsFlavanonesHumansQuality of LifeReactive Oxygen SpeciesCoumaric AcidsFlavanonesnaringinp-coumaric acidReactive Oxygen SpeciesA431AntiproliferativeFlow cytometryNaringinp-coumaric acidSkin cancer

Identifiers

PMID38019336
OpenAlexW4389135957

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.