Evidence map›Paper›PMID 38019016›Full record

ArticleMicrobiology spectrum2024

Co-PATHOgenex web application for assessing complex stress responses in pathogenic bacteria.

Leyden Fernandez, Martin Rosvall, Johan Normark, Maria Fällman, Kemal Avican

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Bacterial stress responses lower mRNA-protein level correlations.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Anti-infective compounds forSustainable microbiology · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Leyden FernandezDepartment of Molecular Biology, Umeå Centre for Microbial Research (UCMR), Umeå University , Umeå, Sweden.
Martin RosvallDepartment of Physics, Integrated Science Lab (Icelab), Umeå University , Umeå, Sweden.
Johan NormarkDepartment of Molecular Biology, Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University , Umeå, Sweden.
Maria FällmanDepartment of Molecular Biology, Umeå Centre for Microbial Research (UCMR), Umeå University , Umeå, Sweden.ORCID 0000-0001-6874-6384
Kemal AvicanDepartment of Molecular Biology, Umeå Centre for Microbial Research (UCMR), Umeå University , Umeå, Sweden.ORCID 0000-0003-0707-2050
Umeå University · SE

Funding

Kempestiftelserna (Kempe Foundations)Knut och Alice Wallenbergs Stiftelse (Knut and Alice Wallenberg Foundation) 2016.0063Vetenskapsrådet (VR) 2018-02855Vetenskapsrådet (VR) 2021-02466
6 · The paper itself

Abstract

importanceUnveiling gene co-expression networks in bacterial pathogens has the potential for gaining insights into their adaptive strategies within the host environment. Here, we developed Co-PATHOgenex, an interactive and user-friendly web application that enables users to construct networks from gene co-expressions using custom-defined thresholds (https://avicanlab.shinyapps.io/copathogenex/). The incorporated search functions and visualizations within the tool simplify the usage and facilitate the interpretation of the analysis output. Co-PATHOgenex also includes stress stimulons for various bacterial species, which can help identify gene products not previously associated with a particular stress condition.

Indexed as

ProteinsSoftwareBacteriaGene Regulatory NetworksRNAProteinsRNAbacterial pathogensgene co-expressiongene regulationRNA-seqstimulonstress responsestranscriptomics

Identifiers

PMID38019016
PMCPMC10783046
OpenAlexW4389136681

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.