Evidence map›Paper›PMID 38018889›Full record

Observational studyClinical cardiology2024

Factors associated with disease progression in patients with atrial fibrillation and heart failure anticoagulated with rivaroxaban.

Nicolás Manito, José María Cepeda-Rodrigo, Nuria Farré, Miguel Castillo Orive, Enrique Galve, Javier Jiménez-Candil, José M García-Pinilla, Eduardo Sebastián López Sánchez, Carles Rafols, Juan José Gómez Doblas

Open access · goldAbstract readObservational StudyMulticenter Study
In one paragraph

Observational study in Clinical cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Nicolás ManitoCardiology Department, Hospital Universitario de Bellvitge, Barcelona, Spain.
José María Cepeda-RodrigoDepartment of Internal Medicine, Hospital Vega Baja, Orihuela, Spain.
Nuria FarréCardiology Department, Hospital del Mar, Barcelona, Spain.
Miguel Castillo OriveCardiology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain.
Enrique GalveConsulta cardiología Galve Basilio, Barcelona, Spain.
Javier Jiménez-CandilCardiology Department, IBSAL-Hospital Universitario de Salamanca, Universidad de Salamanca, CIBER-CV, Salamanca, Spain.ORCID http://orcid.org/0000-0003-1831-8730
José M García-PinillaCardiology Department, Hospital Universitario Virgen de la Victoria, Málaga, Spain.
Eduardo Sebastián López SánchezClínica Cardiología Vera, Almería, Spain.
Carles RafolsMedical Department, Bayer Hispania, Barcelona, Spain.
Juan José Gómez DoblasCardiology Department, Hospital Universitario Virgen de la Victoria, Málaga, Spain.
Instituto de Salud Carlos III · ESBellvitge University Hospital · ESHospital Del Mar · ESHospital Universitario Ramón y Cajal · ESHospital Vega Baja · ESSociedad Española de Cardiología · ESUniversidad de Salamanca · ES

Funding

Bayer Hispania SL
6 · The paper itself

Abstract

backgroundPatients with atrial fibrillation (AF) and heart failure (HF) have a high risk of thromboembolism and other outcomes and anticoagulation is recommended. HYPOTHESIS: This study was aimed to explore the risk factors associated with HF worsening in patients with AF and HF taking rivaroxaban in Spain.

methodsMulticenter, prospective, observational study that included adults with AF and chronic HF, receiving rivaroxaban ≥4 months before entering. HF worsening was defined as first hospitalization or emergency visit because of HF exacerbation.

resultsA total of 672 patients from 71 Spanish centers were recruited, of whom 658 (97.9%) were included in the safety analysis and 552 (82.1%) in the per protocol analysis. At baseline, mean age was 73.7 ± 10.9 years, 64.9% were male, CHA

conclusionsApproximately one out of four patients with HF and AF treated with rivaroxaban developed a HF worsening episode after 2 years of follow-up. The identification of those factors that increase the risk of HF worsening could be helpful in the comprehensive management of this population.

Indexed as

Atrial FibrillationHeart FailureStrokeThromboembolismAdultAgedAged, 80 and overAnticoagulantsDisease ProgressionFemaleHemorrhageHumansMaleMiddle AgedProspective StudiesRivaroxabanAnticoagulantsRivaroxabananticoagulationatrial fibrillationdirect oral anticoagulantheart failurerivaroxabanworsening heart failure

Identifiers

PMID38018889
PMCPMC10823448
OpenAlexW4389138382

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.