Evidence map›Paper›PMID 38018491›Full record

ArticleJournal of the American Heart Association2023

Mortality and Morbidity of Heart Failure Hospitalization in Adult Patients With Congenital Heart Disease.

Pradyumna Agasthi, Holly K Van Houten, Xiaoxi Yao, C Charles Jain, Alexander Egbe, Carole A Warnes, William R Miranda, Shannon M Dunlay, Elizabeth H Stephens, Jonathan N Johnson and 2 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Heart Failure in Adult Congenital Heart Disease.Methodist DeBakey cardiovascular journal · 2026
    Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Discovery and functional investigation ofAmerican journal of translational research · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Pradyumna AgasthiDepartment of Cardiovascular Medicine, Mayo Clinic Rochester MN USA.ORCID 0000-0003-3067-6979
Holly K Van HoutenRobert D. and Patricia E. Kern Center for the Science of Healthcare Delivery, Mayo Clinic Rochester MN USA.ORCID 0000-0003-4981-4868
Xiaoxi YaoRobert D. and Patricia E. Kern Center for the Science of Healthcare Delivery, Mayo Clinic Rochester MN USA.ORCID 0000-0001-9906-7106
C Charles JainDepartment of Cardiovascular Medicine, Mayo Clinic Rochester MN USA.ORCID 0000-0002-1116-8541
Alexander EgbeDepartment of Cardiovascular Medicine, Mayo Clinic Rochester MN USA.ORCID 0000-0002-8810-3631
Carole A WarnesDepartment of Cardiovascular Medicine, Mayo Clinic Rochester MN USA.
William R MirandaDepartment of Cardiovascular Medicine, Mayo Clinic Rochester MN USA.ORCID 0000-0001-8864-8474
Shannon M DunlayDepartment of Cardiovascular Medicine, Mayo Clinic Rochester MN USA.ORCID 0000-0001-5145-7420
Elizabeth H StephensDepartment of Cardiovascular Surgery, Mayo Clinic Rochester MN USA.ORCID 0000-0001-8709-6794
Jonathan N JohnsonDivision of Pediatric Cardiology, Department of Pediatric and Adolescent Medicine, Mayo Clinic Children's Center Rochester MN USA.ORCID 0000-0001-7850-0636
Heidi M ConnollyDepartment of Cardiovascular Medicine, Mayo Clinic Rochester MN USA.ORCID 0000-0003-0666-0344
Luke J BurchillDepartment of Cardiovascular Medicine, Mayo Clinic Rochester MN USA.ORCID 0000-0001-9786-1840

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLittle is known about outcomes following heart failure (HF) hospitalization among adults with congenital heart disease (CHD) in the United States. We aim to compare the outcomes of HF versus non-HF hospitalizations in adults with CHD. METHODS AND

resultsUsing a national deidentified administrative claims data set, patients with adult congenital heart disease (ACHD) hospitalized with and without HF (ACHDHF+, ACHDHF-) were characterized to determine the predictors of 90-day and 1-year mortality and quantify the risk of mortality, major adverse cardiac and cerebrovascular events, and health resource use. Cox proportional hazard regression was used to compare ACHDHF+ versus ACHDHF- for risk of events and health resource use. Of 26 454 unique ACHD admissions between January 1, 2010 and December 31, 2020, 5826 (22%) were ACHDHF+ and 20 628 (78%) were ACHDHF-. The ACHD HF+ hospitalizations increased from 6.6% to 14.0% (

conclusionsHF hospitalization is associated with increased risk of mortality and morbidity with high health resource use in patients with ACHD. Recent cardiology clinic attendance appears to mitigate these risks.

Indexed as

Heart Defects, CongenitalHeart FailureAdultHospitalizationHumansMorbidityPatient ReadmissionUnited Statesadult congenital heart diseaseheart failure hospitalizationmortality

Identifiers

PMID38018491
PMCPMC10727341

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.