Evidence map›Paper›PMID 38018381›Full record

ArticleGenes, brain, and behavior2023

The polygenic and reactive nature of observed parenting.

Jana Runze, Marian J Bakermans-Kranenburg, Charlotte A M Cecil, Marinus H van IJzendoorn, Irene Pappa

Open access · hybridAbstract read
In one paragraph

Article in Genes, brain, and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 5 countries.

Jana RunzeResearch Institute of Child Development and Education, University of Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0003-1792-3357
Marian J Bakermans-KranenburgISPA - University Institute of Psychological, Social and Life Sciences, Lisbon, Portugal.ORCID 0000-0001-7763-0711
Charlotte A M CecilDepartment of Child and Adolescent Psychiatry, Erasmus Medical Center, Rotterdam, the Netherlands.ORCID 0000-0002-2389-5922
Marinus H van IJzendoornDepartment of Psychology, Education and Child Studies, Erasmus University Rotterdam, Rotterdam, the Netherlands.ORCID 0000-0003-1144-454X
Irene PappaDepartment of Child and Adolescent Psychiatry, Erasmus Medical Center, Rotterdam, the Netherlands.ORCID 0000-0003-4936-5791
Erasmus MC · NLDepartment of Health and Social Care · GBNew School · USUniversity of Amsterdam · NL

Funding

Netherlands Organization for Scientific Research 024.001.003
6 · The paper itself

Abstract

In Wertz et al. (2019), parents' polygenic scores of educational attainment (PGS-EA) predicted parental sensitive responses to the child's needs for support, as observed in a dyadic task (i.e., observed sensitivity). We aimed to replicate and expand these findings by combining longitudinal data, child genotype data and several polygenic scores in the Generation R Study. Mother-child dyads participated in two developmental periods, toddlerhood (14 months old; n = 648) and early childhood (3-4 years old, n = 613). Higher maternal PGS-EA scores predicted higher observed sensitivity in toddlerhood (b = 0.12, 95% CI 0.03, 0.20) and early childhood (b = 0.16, 95% CI 0.08, 0.24). Child PGS-EA was significantly associated with maternal sensitivity in early childhood (b = 0.11, 95% CI 0.02, 0.21), and the effect of maternal PGS-EA was no longer significant when correcting for child PGS-EA. A latent factor of PGSs based on educational attainment, intelligence (IQ) and income showed similar results. These polygenic scores might be associated with maternal cognitive and behavioral skills that help shape parenting. Maternal PGSs predicted observed sensitivity over and above the maternal phenotypes, showing an additional role for PGSs in parenting research. In conclusion, we replicated the central finding of Wertz et al. (2019) that parental PGS-EA partially explains parental sensitivity. Our findings may be consistent with evocative gene-environment correlation (rGE), emphasizing the dynamic nature of parenting behavior across time, although further research using family trios is needed to adequately test this hypothesis.

Indexed as

Academic SuccessParentingChild, PreschoolEducational StatusGenotypeHumansInfantParentseducational attainmentevocative gene-environment correlationmaternal sensitivityparenting behaviorpolygenic risk score (PGS)

Identifiers

PMID38018381
PMCPMC10733578
OpenAlexW4389145437

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.