Evidence map›Paper›PMID 38017516›Full record

ReviewExperimental hematology & oncology2023

Immune checkpoint inhibitors for multiple myeloma immunotherapy.

Zhaoyun Liu, Xintong Xu, Hui Liu, Xianghong Zhao, Chun Yang, Rong Fu

Open access · goldAbstract readReview
In one paragraph

Review in Experimental hematology & oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
10.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
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  19. CD34International journal of hematology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Zhaoyun Liu *Department of Hematology, Tianjin Medical University General Hospital, Tianjin, 300052, China.
Xintong Xu *Department of Hematology, Tianjin Medical University General Hospital, Tianjin, 300052, China.
Hui LiuDepartment of Hematology, Tianjin Medical University General Hospital, Tianjin, 300052, China.
Xianghong ZhaoDepartment of Hematology, Tianjin Medical University General Hospital, Tianjin, 300052, China.
Chun YangDepartment of Hematology, Tianjin Medical University General Hospital, Tianjin, 300052, China.
Rong FuDepartment of Hematology, Tianjin Medical University General Hospital, Tianjin, 300052, China. furong8369@tmu.edu.cn.
Tianjin Medical University General Hospital · CN

Funding

Medjaden Academy & Research Foundation for Young Scientists No. MJR20221011the National Natural Science Foundation of China Youth Project 82000219the National Natural Science Foundation of China Youth Project no. 81900131the Tianjin Education Commission Research Project 20140118the Tianjin Education Commission Research Project no. 2018KJ043the Tianjin Key Medical Discipline(Specialty) Construction project TJYXZDXK-028Athe Tianjin Municipal Health Commission Youth Project no. TJWJ2021QN001the Tianjin Municipal Natural Science Foundation 19JCZDJC32900the Tianjin Municipal Natural Science Foundation no. 18JCQNJC80400the Tianjin Science and Technology Planning Project no. 20YFZCSY00060
6 · The paper itself

Abstract

Multiple myeloma (MM) is related to immune disorders, recent studys have revealed that immunotherapy can greatly benefit MM patients. Immune checkpoints can negatively modulate the immune system and are closely associated with immune escape. Immune checkpoint-related therapy has attracted much attention and research in MM. However, the efficacy of those therapies need further improvements. There need more thoughts about the immune checkpoint to translate their use in clinical work. In our review, we aggregated the currently known immune checkpoints and their corresponding ligands, further more we propose various ways of potential translation applying treatment based on immune checkpoints for MM patients.

Indexed as

CTLA-4Immune checkpointMultiple myelomaTIGITtreatment strategy

Identifiers

PMID38017516
PMCPMC10685608
OpenAlexW4389085042

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.