Evidence map›Paper›PMID 38017440›Full record

ArticleBMC pediatrics2023

Early-onset pharyngeal airway collapse in infants: a retrospective single-center study.

Wei Qing, Chen Xun, Nong Guangmin, Li Yan, Jiang Min, Yang Ruimin, Li Chunyan, Zhang Xiaobo, Yi Xiang, Liu Jing

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wei Qing *Department of Pediatrics, the First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China.
Chen Xun *Department of Pediatrics, the First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China.
Nong GuangminDepartment of Pediatrics, the First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China.
Li YanDepartment of Pediatrics, the First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China.
Jiang MinDepartment of Pediatrics, the First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China.
Yang RuiminDepartment of Anesthesiology, the First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China.
Li ChunyanDepartment of Radiology, the First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China.
Zhang XiaoboDepartment of Pediatrics, the First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China.
Yi XiangDepartment of Otolaryngology/Head and Neck Surgery, the First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China.
Liu JingDepartment of Pediatrics, the First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China. nnsj01liujing@126.com.

Funding

Guangxi Clinical Research Center for Pediatric disease AD22035219
6 · The paper itself

Abstract

backgroundEarly-onset pharyngeal airway collapse (PAC) in infants, which presents with onset within 6-months old is relatively rare. This disease has not been given enough attention in clinic. The aim of this study was to explore the clinical features, endoscopic findings and outcomes of early-onset PAC in infants.

methodsThe children of PAC with onset within 6-months old were included. A retrospective study was conducted.

results(1) Total 26 cases were included. The age of onset was neonatal period in 20 cases, 1 to 3-months old in 5 cases, and 4 to 6-months old in 1 case. (2) The main clinical manifestations were noisy breathing (26/26), suprasternal retraction (18/26), snoring (14/26) and hypoxic episode (13/26). (3) Based on the endoscopic findings, collapse at the retropalatal level was most common (24/26). (4) Twelve cases underwent pharyngolaryngeal CT examination, which revealed abnormal findings in 7 cases. (5) Fifteen cases were accompanied with the other airway malformations. (6) In the group with comorbidities of cerebral impairment or craniofacial abnormalities, 1 case was lost to follow up, 4 cases died, and 10 cases survived, in which 9 cases had neurodevelopmental disorders. In the group without comorbidities, 2 cases were lost to follow up, 9 cases survived, in which 1 case had neurodevelopmental disorders. The incidence of poor prognosis including death and neurodevelopmental disorders was significantly higher in the group with comorbidities than that without comorbidities (P<0.01). (7) An symptomatic improvement of PAC was found in the majority of the survived cases (18/19) with age.

conclusionsEarly-onset PAC in infants usually exhibits varying degrees of relief with age, whereas the cases with comorbidities had a poor prognosis.

Indexed as

Neurodevelopmental DisordersSnoringChildComorbidityHumansInfantInfant, NewbornRetrospective StudiesClinical featureComorbidityInfantPharyngeal airway collapsePrognosis

Identifiers

PMID38017440
PMCPMC10683220

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