Evidence map›Paper›PMID 38017364›Full record

ArticleThe Journal of international medical research2023

Serum leptin levels and relationship with maternal weight gain at term among obese and non-obese pregnant women in Enugu, Nigeria: a comparative cross-sectional study.

Joseph Tochukwu Enebe, Nympha Onyinye Enebe, Theresa Ukamaka Nwagha, Ijeoma Angela Meka, Malackay Ezenwaeze Nwankwo, Emmanuel Obiora Izuka, John Okafor Egede, Innocent Anayochukwu Ugwu, Ngozi Ijeoma Okoro, Helen Chioma Okoye and 1 more

Open access · goldAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of international medical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Joseph Tochukwu EnebeDepartment of Obstetrics and Gynaecology, Enugu State University of Science and Technology, College of Medicine/Teaching Hospital, Parklane, Enugu, Nigeria.ORCID 0000-0002-3517-1104
Nympha Onyinye EnebeDepartment of Community Medicine, University of Nigeria Teaching Hospital (UNTH), Ituku Ozalla, Enugu, Nigeria.
Theresa Ukamaka NwaghaDepartment of Haematology and Immunology, University of Nigeria Teaching Hospital (UNTH), Ituku Ozalla, Enugu, Nigeria.
Ijeoma Angela MekaDepartment of Chemical Pathology, College of Medicine, University of Nigeria Teaching Hospital (UNTH), Ituku Ozalla, Enugu, Nigeria.
Malackay Ezenwaeze NwankwoDepartment of Obstetrics and Gynaecology, Enugu State University of Science and Technology, College of Medicine/Teaching Hospital, Parklane, Enugu, Nigeria.
Emmanuel Obiora IzukaDepartment of Obstetrics and Gynaecology, University of Nigeria Teaching Hospital (UNTH), Ituku Ozalla, Enugu, Nigeria.
John Okafor EgedeDepartment of Obstetrics and Gynaecology, Alex Ekwueme Federal University Teaching Hospital, Abakaliki, Nigeria.
Innocent Anayochukwu UgwuDepartment of Obstetrics and Gynaecology, Enugu State University of Science and Technology, College of Medicine/Teaching Hospital, Parklane, Enugu, Nigeria.
Ngozi Ijeoma OkoroDepartment of Chemical Pathology, College of Medicine, Enugu State University of Science and Technology (ESUT), Enugu, Nigeria.
Helen Chioma OkoyeDepartment of Haematology and Immunology, University of Nigeria Teaching Hospital (UNTH), Ituku Ozalla, Enugu, Nigeria.
Chukwuemeka Anthony IyokeDepartment of Obstetrics and Gynaecology, College of Medicine, University of Nigeria Ituku/Ozalla Campus, Enugu State, Nigeria.
University of Nigeria Teaching Hospital · NGEnugu State University of Science and Technology · NGFederal Teaching Hospital Abakaliki · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine and compare the mean maternal serum leptin levels, the prevalence of high serum leptin levels and mean gestational weight gain at term among obese and non-obese pregnant women in Enugu, Nigeria.

methodsThis cross-sectional comparative study enrolled obese and non-obese pregnant women. The serum leptin levels of the women were determined using an enzyme-linked immunosorbent assay kit. Anthropometric and sociodemographic data were obtained and compared. Mean weight gain during pregnancy was determined.

resultsA total of 170 pregnant women were included in the study. The mean ± SD serum leptin level (99.39 ± 50.2 ng/ml) and the prevalence of hyperleptinaemia (81 of 85 patients; 95.3%) among the obese pregnant women at term were significantly higher than those of the non-obese pregnant women (48.98 ± 30.35 ng/ml/65 of 85 patients; 76.5%). The mean percentage weight gain was significantly higher in the non-obese women compared with the obese women at term. The predictors of high maternal serum leptin level at term among the participants were the employment status and levels of education of the participants.

conclusionMaternal serum leptin level, maternal weight gain and prevalence of hyperleptinaemia at term were significantly higher in the obese compared with the non-obese pregnant women.

Indexed as

Gestational Weight GainLeptinBody Mass IndexCross-Sectional StudiesFemaleHumansNigeriaObesityPregnancyPregnant PeopleWeight GainLeptinEnugumaternal weight gainpregnant womenSerum leptin

Identifiers

PMID38017364
PMCPMC10686020
OpenAlexW4389151914

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.