Evidence map›Paper›PMID 38017330›Full record

ArticleObesity surgery2024

Ventricular Remodeling Following Metabolic and Bariatric Surgery Decreases Need for Heart Transplantation: A Predictive Model.

Armaun D Rouhi, Rashikh A Choudhury, Gerard D Hoeltzel, Yazid K Ghanem, Yanik J Bababekov, Alejandro Suarez-Pierre, Arthur Yule, Navin G Vigneshwar, Noel N Williams, Kristoffel R Dumon and 1 more

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Article in Obesity surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Armaun D RouhiDepartment of Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, USA. Armaun.Rouhi@pennmedicine.upenn.edu.ORCID 0000-0002-7724-1457
Rashikh A ChoudhuryDivision of Transplantation, Department of Surgery, University of Colorado Hospital, Aurora, CO, USA.
Gerard D HoeltzelSidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
Yazid K GhanemDepartment of Surgery, Cooper University Hospital, Camden, NJ, USA.
Yanik J BababekovDivision of Transplantation, Department of Surgery, University of Colorado Hospital, Aurora, CO, USA.
Alejandro Suarez-PierreDivision of Transplantation, Department of Surgery, University of Colorado Hospital, Aurora, CO, USA.
Arthur YuleDivision of Transplantation, Department of Surgery, University of Colorado Hospital, Aurora, CO, USA.
Navin G VigneshwarDivision of Transplantation, Department of Surgery, University of Colorado Hospital, Aurora, CO, USA.
Noel N WilliamsDepartment of Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Kristoffel R DumonDepartment of Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Trevor L NydamDivision of Transplantation, Department of Surgery, University of Colorado Hospital, Aurora, CO, USA.
University of Colorado Hospital · USHospital of the University of Pennsylvania · USCooper University Hospital · USThomas Jefferson University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeFor patients with obesity and congestive heart failure (CHF) who require heart transplantation (HT), aggressive weight loss has been associated with ventricular remodeling, or subclinical alterations in left and right ventricular structure that affect systolic function. Many have suggested offering metabolic and bariatric surgery (MBS) for these patients. As such, we evaluated the role of MBS in HT for patients with obesity and CHF using predictive modelling techniques. MATERIALS AND

methodsMarkov decision analysis was performed to simulate the life expectancy of 30,000 patients with concomitant obesity, CHF, and 30% ejection fraction (EF) who were deemed ineligible to be waitlisted for HT unless they achieved a BMI < 35 kg/m

resultsRYGB patients had lower rates of HT and received HT quicker when needed. Base case patients who underwent RYGB gained 2.2 additional mean years survival compared with patients who underwent SG and 10.3 additional mean years survival compared with DE. SG patients gained 6.2 mean years of life compared with DE.

conclusionIn this simulation of 30,000 patients with obesity, CHF, and reduced EF, MBS was associated with improved survival by not only decreasing the need for transplantation due to improvements in EF, but also increasing access to HT when needed due to lower average BMI.

Indexed as

Bariatric SurgeryGastric BypassHeart FailureHeart TransplantationObesity, MorbidGastrectomyHumansObesityRetrospective StudiesTreatment OutcomeVentricular RemodelingBariatric surgeryDecision analysisEjection fractionHeart failureHeart transplantationMarkovObesityVentricular remodeling

Identifiers

PMID38017330
OpenAlexW4389108305

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.