Evidence map›Paper›PMID 38017158›Full record

SynthesisSurgical endoscopy2024

Early versus delayed EUS-guided drainage for postoperative pancreatic fluid collections: a systematic review and meta-analysis.

Tsuyoshi Mukai, Yousuke Nakai, Tsuyoshi Hamada, Saburo Matsubara, Takashi Sasaki, Hirotoshi Ishiwatari, Susumu Hijioka, Hideyuki Shiomi, Mamoru Takenaka, Takuji Iwashita and 5 more

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Surgical endoscopy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 12 institutions in 1 country.

Tsuyoshi Mukai *Department of Gastroenterological Endoscopy, Kanazawa Medical University, 1-1 Daigaku, Uchinada, Kahoku, Ishikawa, 920-0293, Japan. tsuyomukai@yahoo.co.jp.
Yousuke Nakai *Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. ynakai-tky@umin.ac.jp.ORCID 0000-0001-7411-1385
Tsuyoshi HamadaDepartment of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Saburo MatsubaraDepartment of Gastroenterology and Hepatology, Saitama Medical Center, Saitama Medical University, Saitama, Japan.
Takashi SasakiDepartment of Hepato-Biliary-Pancreatic Medicine, The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan.
Hirotoshi IshiwatariDivision of Endoscopy, Shizuoka Cancer Center, Shizuoka, Japan.
Susumu HijiokaDepartment of Hepatobiliary and Pancreatic Oncology, National Cancer Center Japan, Tokyo, Japan.
Hideyuki ShiomiDivision of Gastroenterology and Hepatobiliary and Pancreatic Diseases, Department of Internal Medicine, Hyogo Medical University, Hyogo, Japan.
Mamoru TakenakaDepartment of Gastroenterology and Hepatology, Faculty of Medicine, Kindai University, Osaka, Japan.
Takuji IwashitaFirst Department of Internal Medicine, Gifu University Hospital, Gifu, Japan.
Atsuhiro MasudaDivision of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Hyogo, Japan.
Tomotaka SaitoDepartment of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Hiroyuki Isayama *Department of Gastroenterology, Graduate School of Medicine, Juntendo University, Tokyo, Japan.
Ichiro Yasuda *Third Department of Internal Medicine, University of Toyama, Toyama, Japan.
WONDERFUL Study Group in Japan
Gifu University Hospital · JPJuntendo University · JPSocial Insurance Saitama Chuo Hospital · JPHyogo University · JPKobe University · JPKindai University · JPShizuoka Cancer Center · JPThe Cancer Institute Hospital · JPThe University of Tokyo · JPUniversity of Toyama · JPKanazawa Medical University · JPUniversity of Tokyo Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostoperative pancreatic fluid collections (POPFCs) are common adverse events (AEs) after pancreatic surgery and may need interventions. Endoscopic ultrasound (EUS)-guided drainage for POPFCs is increasingly reported, but its appropriate timing has not been fully elucidated. The aim of this meta-analysis was to evaluate treatment outcomes of POPFCs according to the timing of EUS-guided drainage.

methodsUsing PubMed, Embase, Web of Science, and the Cochrane database, we identified clinical studies published until December 2022 with data comparing outcomes of early and delayed EUS-guided drainage for POPFCs. We pooled data on AEs, mortality, and technical and clinical success rates, using the random-effects model.

resultsFrom 1415 papers identified in the initial literature search, we identified 6 retrospective studies, including 128 and 107 patients undergoing early and delayed EUS-guided drainage for POPFCs. The threshold of early and delayed drainage ranged from 14 to 30 days. Distal pancreatectomy was the major cause of POPFCs, ranging from 44 to 100%. The pooled odds ratio (OR) for AEs was 0.81 (95% confidence interval [CI] 0.40-1.64, P = 0.55) comparing early to delayed drainage. There was no procedure-related mortality. Technical success was achieved in all cases and a pooled OR of clinical success was 0.60 (95% CI 0.20-1.83, P = 0.37).

conclusionPOPFCs can be managed by early EUS-guided drainage without an increase in AEs.

Indexed as

EndosonographyPancreatic DiseasesDrainageHumansPancreatectomyRetrospective StudiesTreatment OutcomeUltrasonography, InterventionalDrainageEndoscopic ultrasoundFluid collectionPostoperative pancreatic fistula

Identifiers

PMID38017158
PMCPMC10776699
OpenAlexW4389080423

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.