Evidence map›Paper›PMID 38017118›Full record

ArticleJournal, genetic engineering & biotechnology2023

Enhancement effect of AgO nanoparticles on fermentative cellulase activity from thermophilic Bacillus subtilis Ag-PQ.

Saddam Hussain, Muhammad Talha Yasin, Khurshid Ahmad, Suleman Khan, Rasheed Ahmad, Jallat Khan, Abdul Ghani, Muhammad Musaddiq Shah, Muzzamil Ahmed, Hasnat Tariq and 4 more

Open access · diamondAbstract read
In one paragraph

Article in Journal, genetic engineering & biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 2 countries.

Saddam Hussain *Department of Biological Sciences, International Islamic University, Islamabad, 44000, Pakistan.
Muhammad Talha YasinInstitute of Biological Sciences, Khwaja Fareed University of Engineering and Information Technology, Rahim Yar Khan, 64200, Pakistan.ORCID http://orcid.org/0000-0003-0161-1826
Khurshid Ahmad *Department of Biological Sciences, International Islamic University, Islamabad, 44000, Pakistan. khurshidahmad694@yahoo.com.ORCID http://orcid.org/0000-0002-8809-0228
Suleman KhanDepartment of Physics, NFC Institute of Engineering and Technology, Multan, 60000, Pakistan.
Rasheed AhmadDepartment of Chemical Engineering, University of Engineering & Technology (UET), Peshawar, Khyber Pakhtunkhwa, 25120, Pakistan.
Jallat KhanInstitute of Biological Sciences, Khwaja Fareed University of Engineering and Information Technology, Rahim Yar Khan, 64200, Pakistan.ORCID http://orcid.org/0000-0002-8251-7745
Abdul GhaniDepartment of Biological Sciences, International Islamic University, Islamabad, 44000, Pakistan.
Muhammad Musaddiq ShahDepartment of Biological Sciences, Faculty of Sciences, University of Sialkot, Sialkot, Punjab, 51040, Pakistan.
Muzzamil AhmedDepartment of Biological Sciences, International Islamic University, Islamabad, 44000, Pakistan.
Hasnat TariqDepartment of Biological Sciences, International Islamic University, Islamabad, 44000, Pakistan.
Hamid RehmanDepartment of Environmental Sciences, Quaid-i-Azam University, Islamabad, 45320, Pakistan.
Adil HussainFood and Biotechnology Research Centre (FBRC), Pakistan Council of Scientific and Industrial Research (PCSIR), Laboratories Complex, Ferozepur Road, Lahore, 56400, Pakistan.
Muhammad FaheemDepartment of Biological Sciences, International Islamic University, Islamabad, 44000, Pakistan.
Syed Ali Imran BokhariDepartment of Biological Sciences, International Islamic University, Islamabad, 44000, Pakistan.
International Islamic University, Islamabad · PKKhwaja Fareed University of Engineering and Information Technology · PKNFC Institute of Engineering and TechnologyPakistan Council of Scientific & Industrial Research · PKQuaid-i-Azam University · PKUniversity of Engineering and Technology Peshawar · PKUniversity of Sialkot

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCellulase is an important bioprocessing enzyme used in various industries. This study was conducted with the aim of improving the biodegradation activity of cellulase obtained from the Bacillus subtilis AG-PQ strain. For this purpose, AgO and FeO NPs were fabricated using AgNO

resultsCultural parameters were optimized to achieve better cellulase production, where incubation time of 56 h, inoculum size of 5%, 1% coconut cake, 0.43% ammonium nitrate, pH 8, and 37 °C temperature were found optimal. The enhancing effect of AgO NPs was observed on cellulase activity (57.804 U/ml/min) at 50 ppm concentration while FeO NPs exhibited an inhibitory effect on cellulase activity at all concentrations. Molecular docking analysis was also performed to understand the underlying mechanism of improved enzymatic activity by nanocatalysts.

conclusionThis study authenticates AgO NPs as better nanocatalysts for improved thermostable cellulase biodegradation activity with the extraordinary capability to be potentially utilized in bioethanol production.

Indexed as

AgO FeO NPsBacillus subtilisCellulaseIndustrial applicationsNanocatalyst

Identifiers

PMID38017118
PMCPMC10684452
OpenAlexW4389109338

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.