Evidence map›Paper›PMID 38017104›Full record

ArticleLeukemia2024

SRSF2 mutation cooperates with ASXL1 truncated alteration to accelerate leukemogenesis.

Pinpin Sui, Guo Ge, Shi Chen, Jiaojiao Bai, Ivan P Rubalcava, Hui Yang, Ying Guo, Peng Zhang, Ying Li, Edward A Medina and 4 more

Abstract readLetter
In one paragraph

Article in Leukemia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. U2af1Leukemia · 2026
    Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Pinpin Sui *Department of Cell Systems & Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.ORCID http://orcid.org/0000-0003-3779-9592
Guo Ge *Department of Cell Systems & Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.ORCID http://orcid.org/0000-0002-6362-772X
Shi ChenDepartment of Molecular Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
Jiaojiao BaiDepartment of Cell Systems & Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
Ivan P RubalcavaDepartment of Cell Systems & Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.ORCID http://orcid.org/0000-0003-1749-3799
Hui YangDepartment of Cell Systems & Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
Ying GuoDepartment of Cell Systems & Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
Peng ZhangDepartment of Cell Systems & Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.ORCID http://orcid.org/0000-0002-3394-6922
Ying LiDepartment of Molecular Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
Edward A MedinaDepartment of Pathology and Laboratory Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
Mingjiang XuMays Cancer Center, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.ORCID http://orcid.org/0000-0002-7063-6253
Omar Abdel-WahabHuman Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Robert BradleyComputational Biology Program, Public Health Sciences Division and Basic Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-8046-1063
Feng-Chun YangDepartment of Cell Systems & Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA. yangf1@uthscsa.edu.ORCID http://orcid.org/0000-0001-8524-4095

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Genetic and molecular basis for SRSF2 mutations in myelodysplasiaR01HL128239 · NHLBI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Omar Abdel-Wahab, Robert K Bradley · 2015 to 2026
$8.0M
Role of Asxl1 in normal hematopoiesis and pathogenesis of myeloid malignanciesR01CA172408 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI XU, MINGJIANG, YANG, FENG-CHUN · 2014 to 2024
$3.4M
Roles of TET2-dependent DNA demethylation intermediates in hematological malignanciesR01HL145883 · NHLBI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI XU, MINGJIANG, YANG, FENG-CHUN · 2019 to 2022
$2.2M
Role of BRD4 in Normal Hematopoiesis and Hematopoietic Stem Cell Biology_R01HL158081 · NHLBI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI YANG, FENG-CHUN · 2022 to 2024
$1.1M
Role of PHF6 in Normal Hematopoiesis and hematopoietic stem cell biologyR01HL149318 · NHLBI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI YANG, FENG-CHUN · 2019 to 2021
$925k
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA172408NHLBI NIH HHS R01 HL128239NHLBI NIH HHS R01 HL145883NHLBI NIH HHS R01 HL149318NHLBI NIH HHS R01 HL158081
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

LeukemiaHumansMutationRepressor ProteinsSerine-Arginine Splicing FactorsTranscription FactorsASXL1 protein, humanRepressor ProteinsSerine-Arginine Splicing FactorsSRSF2 protein, humanTranscription Factors

Identifiers

PMID38017104
PMCPMC10844088

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.