Evidence map›Paper›PMID 38017092›Full record

ArticleScientific reports2023

Comparative analyses of the faecal resistome against β-lactam and quinolone antibiotics in humans and livestock using metagenomic sequencing.

Jieun Kim, Youna Cho, Suk-Kyung Lim, Mi-Ran Seo, Jang Won Sohn, Bongyoung Kim, Mina Rho, Hyunjoo Pai

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jieun Kim *Department of Internal Medicine, College of Medicine, Hanyang University, Seoul, 04763, Republic of Korea.
Youna Cho *Department of Computer Science and Engineering, Hanyang University, Seoul, 04763, Republic of Korea.
Suk-Kyung Lim *Bacterial Disease Division, Animal and Plant Quarantine Agency, 177 Hyeokin 8-ro, Gimcheon-si, Gyeongsangbuk-do, 39660, Republic of Korea.
Mi-Ran SeoConnectaGen Inc., F 203, MisaCentumbiz 2F, Jojeong-Dearo, Hanam-si, Gyeonggi-do, 12918, Republic of Korea.
Jang Won SohnDepartment of Internal Medicine, College of Medicine, Hanyang University, Seoul, 04763, Republic of Korea.
Bongyoung KimDepartment of Internal Medicine, College of Medicine, Hanyang University, Seoul, 04763, Republic of Korea.
Mina Rho *Department of Computer Science and Engineering, Hanyang University, Seoul, 04763, Republic of Korea. minarho@hanyang.ac.kr.
Hyunjoo Pai *Department of Internal Medicine, College of Medicine, Hanyang University, Seoul, 04763, Republic of Korea. paihyunjoo@gmail.com.
Hanyang University · KRAnimal and Plant Quarantine Agency · KR

Funding

National Research Foundation of Korea 2015R1C1A1A01055646Research of Korea Centers for Disease Control and Prevention 2017ER540702
6 · The paper itself

Abstract

To assess the prevalence and abundance of antibiotic resistance genes in human and livestock gut microbiomes, 87 humans (healthy individuals and patients with Clostridioides difficile infection (CDI)) and 108 livestock (swine, cattle, and chickens) were enrolled. Gut microbiomes and fluoroquinolone-resistant Escherichia coli isolates were sequenced, and mobile genetic elements adjacent to the β-lactamase (bla) and transferable quinolone resistance (qnr) genes were compared using metagenomic contigs. Each group of humans and livestock exhibited distinctive microbiota and resistome compositions in the gut. Concerning the resistome of bla and qnr, the prevalence rates between chickens and patients with CDI were the most similar (R

Indexed as

beta-LactamsQuinolonesAnimalsAnti-Bacterial Agentsbeta-LactamasesCattleChickensEscherichia coliHumansLivestockPhylogenyPlasmidsSwineAnti-Bacterial Agentsbeta-Lactamasesbeta-LactamsQuinolones

Identifiers

PMID38017092
PMCPMC10684531
OpenAlexW4389079639

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.