Evidence map›Paper›PMID 38017078›Full record

ArticleScientific reports2023

Maternal early mid-pregnancy adiponectin in relation to infant birth weight and the likelihood of being born large-for-gestational-age.

Emelie Lindberger, Anders Larsson, Theodora Kunovac Kallak, Inger Sundström Poromaa, Anna-Karin Wikström, Anna Österroos, Fredrik Ahlsson

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Emelie LindbergerDepartment of Women's and Children's Health, Uppsala University, 751 85, Uppsala, Sweden. emelie.lindberger@kbh.uu.se.ORCID 0000-0002-4020-3158
Anders LarssonDepartment of Medical Sciences, Uppsala University, 751 85, Uppsala, Sweden.
Theodora Kunovac KallakDepartment of Women's and Children's Health, Uppsala University, 751 85, Uppsala, Sweden.
Inger Sundström PoromaaDepartment of Women's and Children's Health, Uppsala University, 751 85, Uppsala, Sweden.
Anna-Karin WikströmDepartment of Women's and Children's Health, Uppsala University, 751 85, Uppsala, Sweden.
Anna ÖsterroosDepartment of Women's and Children's Health, Uppsala University, 751 85, Uppsala, Sweden.
Fredrik AhlssonDepartment of Women's and Children's Health, Uppsala University, 751 85, Uppsala, Sweden.
Uppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate the association of maternal adiponectin with infant birth size in 1349 pregnant women at Uppsala University Hospital, Sweden. The mean age of the women was 31.0 years, and 40.9% were nulliparous. Maternal early mid-pregnancy adiponectin was measured in microgram/mL. Linear regression models were performed to evaluate the association between adiponectin and infant birth weight. Logistic regression models were used to evaluate adiponectin in relation to the odds of giving birth to an infant large-for-gestational-age (LGA, infant birth weight standard deviation score > 90th percentile). Adjustments were made for early pregnancy BMI and diabetes mellitus. Prior adjustments, adiponectin was inversely associated with infant birth weight (β - 17.1, 95% confidence interval (CI) - 26.8 to - 7.4 g, P < 0.001), and one microgram/mL increase in adiponectin was associated with a 9% decrease in the odds of giving birth to an LGA infant (odds ratio 0.91, CI 0.85-0.97, P = 0.006). The associations did not withstand in the adjusted models. We found a significant interaction between adiponectin and infant sex on birth size. This interaction was driven by an inverse association between maternal adiponectin and birth size in female infants, whereas no such association was found in males.

Indexed as

AdiponectinDiabetes MellitusAdultBirth WeightFemaleHumansInfantInfant, Large for Gestational AgeMaleParityPregnancyAdiponectin

Identifiers

PMID38017078
PMCPMC10684871
OpenAlexW4389098087

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.