Evidence map›Paper›PMID 38017015›Full record

ArticleScientific reports2023

Single cell and spatial transcriptomics analysis of kidney double negative T lymphocytes in normal and ischemic mouse kidneys.

Sepideh Gharaie, Kyungho Lee, Kathleen Noller, Emily K Lo, Brendan Miller, Hyun Jun Jung, Andrea M Newman-Rivera, Johanna T Kurzhagen, Nirmish Singla, Paul A Welling and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 15 citations in OpenAlex.

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  12. New approaches to acute kidney injury.Clinical kidney journal · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Sepideh GharaieDepartment of Medicine, Johns Hopkins University, School of Medicine, Ross 965, 720 Rutland Ave, Baltimore, MD, 21205, USA.
Kyungho LeeDepartment of Medicine, Johns Hopkins University, School of Medicine, Ross 965, 720 Rutland Ave, Baltimore, MD, 21205, USA.
Kathleen NollerDepartment of Biomedical Engineering, Johns Hopkins University, School of Medicine, Baltimore, MD, 21205, USA.
Emily K LoDepartment of Biomedical Engineering, Johns Hopkins University, School of Medicine, Baltimore, MD, 21205, USA.
Brendan MillerDepartment of Biomedical Engineering, Johns Hopkins University, School of Medicine, Baltimore, MD, 21205, USA.
Hyun Jun JungDepartment of Medicine, Johns Hopkins University, School of Medicine, Ross 965, 720 Rutland Ave, Baltimore, MD, 21205, USA.
Andrea M Newman-RiveraDepartment of Medicine, Johns Hopkins University, School of Medicine, Ross 965, 720 Rutland Ave, Baltimore, MD, 21205, USA.
Johanna T KurzhagenDepartment of Medicine, Johns Hopkins University, School of Medicine, Ross 965, 720 Rutland Ave, Baltimore, MD, 21205, USA.
Nirmish SinglaDepartment of Urology, Johns Hopkins University, School of Medicine, Baltimore, MD, 21205, USA.
Paul A WellingDepartment of Medicine, Johns Hopkins University, School of Medicine, Ross 965, 720 Rutland Ave, Baltimore, MD, 21205, USA.
Jean FanDepartment of Biomedical Engineering, Johns Hopkins University, School of Medicine, Baltimore, MD, 21205, USA.
Patrick CahanDepartment of Biomedical Engineering, Johns Hopkins University, School of Medicine, Baltimore, MD, 21205, USA.
Sanjeev NoelDepartment of Medicine, Johns Hopkins University, School of Medicine, Ross 965, 720 Rutland Ave, Baltimore, MD, 21205, USA.
Hamid RabbDepartment of Medicine, Johns Hopkins University, School of Medicine, Ross 965, 720 Rutland Ave, Baltimore, MD, 21205, USA. hrabb1@jhmi.edu.
Johns Hopkins Medicine · USJohns Hopkins University · US

Funding

KPMP Kidney Mapping and Atlas Project (KMAP)U01DK133090 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jonathan Himmelfarb, Matthias Kretzler · 2022 to 2026
$10.4M
From intra to intercellular regulatory networks that define cell type identityR35GM124725 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI Patrick Cahan · 2017 to 2026
$4.5M
Acute Kidney Injury and Double Negative T CellsR01DK104662 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI HAMAD, ABDEL RAHIM, RABB, HAMID · 2015 to 2023
$3.8M
Acute kidney injury and microbiomeR01DK123342 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI RABB, HAMID · 2020 to 2024
$3.0M
Computational methods for delineating subcellular and cellular spatial transcriptional heterogeneity along developmental trajectoriesR35GM142889 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI FAN, JEAN · 2021 to 2025
$2.0M
NIDDK NIH HHS R01 DK104662NIDDK NIH HHS R01DK104662NIDDK NIH HHS R01 DK123342NIDDK NIH HHS R01DK123342NIDDK NIH HHS U01 DK133090NIGMS NIH HHS R35 GM124725NIGMS NIH HHS R35 GM142889
6 · The paper itself

Abstract

T cells are important in the pathogenesis of acute kidney injury (AKI), and TCR

Indexed as

Acute Kidney InjuryCD8-Positive T-LymphocytesAnimalsCD4 AntigensCD8 AntigensHumansKidneyMiceReceptors, Antigen, T-Cell, alpha-betaTranscriptomeCD4 AntigensCD8 AntigensReceptors, Antigen, T-Cell, alpha-beta

Identifiers

PMID38017015
PMCPMC10684868
OpenAlexW4389087630

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.