Evidence map›Paper›PMID 38016726›Full record

ArticleCanadian journal of surgery. Journal canadien de chirurgie

Should advanced donor age be a deterrent in the utilization of grafts from donation after cardiac death in deceased donor liver transplantation? The Toronto experience.

Samrat Ray, Chaya Shwaartz, Blayne Amir Sayed, Gonzalo Sapisochin, Anand Ghanekar, Ian McGilvray, Mark Cattral, Leslie Lilly, Nazia Selzner, Cynthia Tsien and 4 more

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Article in Canadian journal of surgery. Journal canadien de chirurgie. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Samrat RayFrom the Ajmera Transplant Centre, Toronto General Hospital, University Health Network, Toronto, Ont. (Ray, Schwaartz, Sayed, Sapisochin, Ghanekar, McGilvray, Cattral, Lilly, N. Selzner, Tsien, Bhat, Jaeckel, M. Selzner, Reichman); and the Department of Surgery, University of Toronto, Toronto, Ont. (Schwaartz, Sayed, Sapisochin, Ghanekar, McGilvray, Cattral, Lilly, N. Selzner, Tsien, Bhat, Jaeckel, M. Selzner, Reichman).
Chaya ShwaartzFrom the Ajmera Transplant Centre, Toronto General Hospital, University Health Network, Toronto, Ont. (Ray, Schwaartz, Sayed, Sapisochin, Ghanekar, McGilvray, Cattral, Lilly, N. Selzner, Tsien, Bhat, Jaeckel, M. Selzner, Reichman); and the Department of Surgery, University of Toronto, Toronto, Ont. (Schwaartz, Sayed, Sapisochin, Ghanekar, McGilvray, Cattral, Lilly, N. Selzner, Tsien, Bhat, Jaeckel, M. Selzner, Reichman).
Blayne Amir SayedFrom the Ajmera Transplant Centre, Toronto General Hospital, University Health Network, Toronto, Ont. (Ray, Schwaartz, Sayed, Sapisochin, Ghanekar, McGilvray, Cattral, Lilly, N. Selzner, Tsien, Bhat, Jaeckel, M. Selzner, Reichman); and the Department of Surgery, University of Toronto, Toronto, Ont. (Schwaartz, Sayed, Sapisochin, Ghanekar, McGilvray, Cattral, Lilly, N. Selzner, Tsien, Bhat, Jaeckel, M. Selzner, Reichman).
Gonzalo SapisochinFrom the Ajmera Transplant Centre, Toronto General Hospital, University Health Network, Toronto, Ont. (Ray, Schwaartz, Sayed, Sapisochin, Ghanekar, McGilvray, Cattral, Lilly, N. Selzner, Tsien, Bhat, Jaeckel, M. Selzner, Reichman); and the Department of Surgery, University of Toronto, Toronto, Ont. (Schwaartz, Sayed, Sapisochin, Ghanekar, McGilvray, Cattral, Lilly, N. Selzner, Tsien, Bhat, Jaeckel, M. Selzner, Reichman).
Anand GhanekarFrom the Ajmera Transplant Centre, Toronto General Hospital, University Health Network, Toronto, Ont. (Ray, Schwaartz, Sayed, Sapisochin, Ghanekar, McGilvray, Cattral, Lilly, N. Selzner, Tsien, Bhat, Jaeckel, M. Selzner, Reichman); and the Department of Surgery, University of Toronto, Toronto, Ont. (Schwaartz, Sayed, Sapisochin, Ghanekar, McGilvray, Cattral, Lilly, N. Selzner, Tsien, Bhat, Jaeckel, M. Selzner, Reichman).
Ian McGilvrayFrom the Ajmera Transplant Centre, Toronto General Hospital, University Health Network, Toronto, Ont. (Ray, Schwaartz, Sayed, Sapisochin, Ghanekar, McGilvray, Cattral, Lilly, N. Selzner, Tsien, Bhat, Jaeckel, M. Selzner, Reichman); and the Department of Surgery, University of Toronto, Toronto, Ont. (Schwaartz, Sayed, Sapisochin, Ghanekar, McGilvray, Cattral, Lilly, N. Selzner, Tsien, Bhat, Jaeckel, M. Selzner, Reichman).
Mark CattralFrom the Ajmera Transplant Centre, Toronto General Hospital, University Health Network, Toronto, Ont. (Ray, Schwaartz, Sayed, Sapisochin, Ghanekar, McGilvray, Cattral, Lilly, N. Selzner, Tsien, Bhat, Jaeckel, M. Selzner, Reichman); and the Department of Surgery, University of Toronto, Toronto, Ont. (Schwaartz, Sayed, Sapisochin, Ghanekar, McGilvray, Cattral, Lilly, N. Selzner, Tsien, Bhat, Jaeckel, M. Selzner, Reichman).
Leslie LillyFrom the Ajmera Transplant Centre, Toronto General Hospital, University Health Network, Toronto, Ont. (Ray, Schwaartz, Sayed, Sapisochin, Ghanekar, McGilvray, Cattral, Lilly, N. Selzner, Tsien, Bhat, Jaeckel, M. Selzner, Reichman); and the Department of Surgery, University of Toronto, Toronto, Ont. (Schwaartz, Sayed, Sapisochin, Ghanekar, McGilvray, Cattral, Lilly, N. Selzner, Tsien, Bhat, Jaeckel, M. Selzner, Reichman).
Nazia SelznerFrom the Ajmera Transplant Centre, Toronto General Hospital, University Health Network, Toronto, Ont. (Ray, Schwaartz, Sayed, Sapisochin, Ghanekar, McGilvray, Cattral, Lilly, N. Selzner, Tsien, Bhat, Jaeckel, M. Selzner, Reichman); and the Department of Surgery, University of Toronto, Toronto, Ont. (Schwaartz, Sayed, Sapisochin, Ghanekar, McGilvray, Cattral, Lilly, N. Selzner, Tsien, Bhat, Jaeckel, M. Selzner, Reichman).
Cynthia TsienFrom the Ajmera Transplant Centre, Toronto General Hospital, University Health Network, Toronto, Ont. (Ray, Schwaartz, Sayed, Sapisochin, Ghanekar, McGilvray, Cattral, Lilly, N. Selzner, Tsien, Bhat, Jaeckel, M. Selzner, Reichman); and the Department of Surgery, University of Toronto, Toronto, Ont. (Schwaartz, Sayed, Sapisochin, Ghanekar, McGilvray, Cattral, Lilly, N. Selzner, Tsien, Bhat, Jaeckel, M. Selzner, Reichman).
Mamatha BhatFrom the Ajmera Transplant Centre, Toronto General Hospital, University Health Network, Toronto, Ont. (Ray, Schwaartz, Sayed, Sapisochin, Ghanekar, McGilvray, Cattral, Lilly, N. Selzner, Tsien, Bhat, Jaeckel, M. Selzner, Reichman); and the Department of Surgery, University of Toronto, Toronto, Ont. (Schwaartz, Sayed, Sapisochin, Ghanekar, McGilvray, Cattral, Lilly, N. Selzner, Tsien, Bhat, Jaeckel, M. Selzner, Reichman).
Elmar JaeckelFrom the Ajmera Transplant Centre, Toronto General Hospital, University Health Network, Toronto, Ont. (Ray, Schwaartz, Sayed, Sapisochin, Ghanekar, McGilvray, Cattral, Lilly, N. Selzner, Tsien, Bhat, Jaeckel, M. Selzner, Reichman); and the Department of Surgery, University of Toronto, Toronto, Ont. (Schwaartz, Sayed, Sapisochin, Ghanekar, McGilvray, Cattral, Lilly, N. Selzner, Tsien, Bhat, Jaeckel, M. Selzner, Reichman).
Markus SelznerFrom the Ajmera Transplant Centre, Toronto General Hospital, University Health Network, Toronto, Ont. (Ray, Schwaartz, Sayed, Sapisochin, Ghanekar, McGilvray, Cattral, Lilly, N. Selzner, Tsien, Bhat, Jaeckel, M. Selzner, Reichman); and the Department of Surgery, University of Toronto, Toronto, Ont. (Schwaartz, Sayed, Sapisochin, Ghanekar, McGilvray, Cattral, Lilly, N. Selzner, Tsien, Bhat, Jaeckel, M. Selzner, Reichman).
Trevor W ReichmanFrom the Ajmera Transplant Centre, Toronto General Hospital, University Health Network, Toronto, Ont. (Ray, Schwaartz, Sayed, Sapisochin, Ghanekar, McGilvray, Cattral, Lilly, N. Selzner, Tsien, Bhat, Jaeckel, M. Selzner, Reichman); and the Department of Surgery, University of Toronto, Toronto, Ont. (Schwaartz, Sayed, Sapisochin, Ghanekar, McGilvray, Cattral, Lilly, N. Selzner, Tsien, Bhat, Jaeckel, M. Selzner, Reichman) trevor.reichman@uhn.ca.
University of Toronto · CAToronto General Hospital · CAUniversity Health Network · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdvanced donor age paired with donation after cardiac death (DCD) increases the risk of transplantation, precluding widespread use of grafts from such donors worldwide. Our aim was to analyze outcomes of liver transplantation using grafts from older DCD donors and donation after brain death (DBD) donors.

methodsPatients who underwent liver transplantation using grafts from deceased donors between January 2016 and December 2021 were included in the study. Short-and long-term outcomes were analyzed for 4 groups of patients: those who received DCD and DBD grafts from younger (< 50 yr) and older (≥ 50 yr) donors.

resultsOf the 807 patients included in the analysis, 44.7% (

conclusionDonor age alone should not be the criterion to determine the acceptability of grafts in liver transplantation. With careful selection criteria, older DCD donors could make a valuable contribution to expanding the liver donor pool, with grafts that produce comparable results to those obtained with standard-criteria grafts.

Indexed as

Liver TransplantationTissue and Organ ProcurementBrain DeathConstriction, PathologicDeathHumansLiving DonorsRetrospective StudiesTissue Donors

Identifiers

PMID38016726
PMCPMC10699285
OpenAlexW4389114722

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.