Evidence map›Paper›PMID 38016693›Full record

ArticleACS applied bio materials2023

Modern Photodynamic Glioblastoma Therapy Using Curcumin- or Parietin-Loaded Lipid Nanoparticles in a CAM Model Study.

Jan Schulze, Lisa Schöne, Abdallah M Ayoub, Damiano Librizzi, Muhammad Umair Amin, Konrad Engelhardt, Behrooz H Yousefi, Lena Bender, Jens Schaefer, Eduard Preis and 3 more

Open access · greenAbstract read
In one paragraph

Article in ACS applied bio materials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Jan SchulzeDepartment of Pharmaceutics and Biopharmaceutics, University of Marburg, Robert-Koch-Strasse 4, Marburg 35037, Germany.ORCID 0000-0002-9005-9000
Lisa SchöneInstitute of Pharmacy, Pharmaceutical Technology, Faculty of Medicine, Leipzig University, Eilenburger Strasse 15a, Leipzig 04317, Germany.
Abdallah M AyoubDepartment of Pharmaceutics and Biopharmaceutics, University of Marburg, Robert-Koch-Strasse 4, Marburg 35037, Germany.
Damiano LibrizziCenter for Tumor Biology and Immunology (ZTI), Core Facility Molecular Imaging, Department of Nuclear Medicine, University of Marburg, Hans-Meerwein-Strasse 3, Marburg 35043, Germany.
Muhammad Umair AminDepartment of Pharmaceutics and Biopharmaceutics, University of Marburg, Robert-Koch-Strasse 4, Marburg 35037, Germany.
Konrad EngelhardtDepartment of Pharmaceutics and Biopharmaceutics, University of Marburg, Robert-Koch-Strasse 4, Marburg 35037, Germany.
Behrooz H YousefiCenter for Tumor Biology and Immunology (ZTI), Core Facility Molecular Imaging, Department of Nuclear Medicine, University of Marburg, Hans-Meerwein-Strasse 3, Marburg 35043, Germany.ORCID 0000-0003-0679-4449
Lena BenderDepartment of Pharmaceutics and Biopharmaceutics, University of Marburg, Robert-Koch-Strasse 4, Marburg 35037, Germany.
Jens SchaeferDepartment of Pharmaceutics and Biopharmaceutics, University of Marburg, Robert-Koch-Strasse 4, Marburg 35037, Germany.ORCID 0000-0002-4043-6912
Eduard PreisDepartment of Pharmaceutics and Biopharmaceutics, University of Marburg, Robert-Koch-Strasse 4, Marburg 35037, Germany.ORCID 0000-0003-2112-8436
Michaela Schulz-SiegmundInstitute of Pharmacy, Pharmaceutical Technology, Faculty of Medicine, Leipzig University, Eilenburger Strasse 15a, Leipzig 04317, Germany.ORCID 0000-0003-1340-1850
Christian WölkInstitute of Pharmacy, Pharmaceutical Technology, Faculty of Medicine, Leipzig University, Eilenburger Strasse 15a, Leipzig 04317, Germany.ORCID 0000-0002-8067-7307
Udo BakowskyDepartment of Pharmaceutics and Biopharmaceutics, University of Marburg, Robert-Koch-Strasse 4, Marburg 35037, Germany.ORCID 0000-0002-3895-0453
Philipps University of Marburg · DELeipzig University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural photosensitizers, such as curcumin or parietin, play a vital role in photodynamic therapy (PDT), causing a light-mediated reaction that kills cancer cells. PDT is a promising treatment option for glioblastoma, especially when combined with nanoscale drug delivery systems. The curcumin- or parietin-loaded lipid nanoparticles were prepared via dual asymmetric centrifugation and subsequently characterized through physicochemical analyses including dynamic light scattering, laser Doppler velocimetry, and atomic force microscopy. The combination of PDT and lipid nanoparticles has been evaluated

Indexed as

CurcuminGlioblastomaPhotochemotherapyAnimalsCell Line, TumorChickensEmodinFemaleHumansLiposomesNanoparticlesCurcuminEmodinLipid NanoparticlesLiposomesphyscione3D cell cultureCAM modeldrug delivery systemdual asymmetric centrifugationlipid nanoparticlesnatural photosensitizer

Identifiers

PMID38016693
PMCPMC10732153
OpenAlexW4389108918

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.