Evidence map›Paper›PMID 38016062›Full record

ArticleACS nano2024

Immunomodulatory Nanoparticles for Modulating Arthritis Flares.

Wade T Johnson, David McBride, Matthew Kerr, Anders Nguyen, Martina Zoccheddu, Miriam Bollmann, Xiaofu Wei, Ryan M Jones, Wei Wang, Mattias N D Svensson and 2 more

Open access · greenAbstract read
In one paragraph

Article in ACS nano, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Wade T JohnsonDepartment of NanoEngineering and Chemical Engineering Program, University of California, San Diego, La Jolla, California 92093, United States.ORCID 0000-0002-0810-6454
David McBrideDepartment of NanoEngineering and Chemical Engineering Program, University of California, San Diego, La Jolla, California 92093, United States.
Matthew KerrDepartment of NanoEngineering and Chemical Engineering Program, University of California, San Diego, La Jolla, California 92093, United States.
Anders NguyenDepartment of Rheumatology and Inflammation Research, University of Gothenburg, Gothenburg 41346, Sweden.
Martina ZocchedduDepartment of Medicine, University of California, San Diego, La Jolla, California 92093, United States.
Miriam BollmannDepartment of Rheumatology and Inflammation Research, University of Gothenburg, Gothenburg 41346, Sweden.
Xiaofu WeiDepartment of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California 92093, United States.
Ryan M JonesDepartment of NanoEngineering and Chemical Engineering Program, University of California, San Diego, La Jolla, California 92093, United States.
Wei WangDepartment of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California 92093, United States.
Mattias N D SvenssonDepartment of Rheumatology and Inflammation Research, University of Gothenburg, Gothenburg 41346, Sweden.ORCID 0000-0001-8077-9824
Nunzio BottiniKao Autoimmunity Institute and Division of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, California 90048, United States.
Nisarg J ShahDepartment of NanoEngineering and Chemical Engineering Program, University of California, San Diego, La Jolla, California 92093, United States.ORCID 0000-0003-1727-5732
University of California San Diego · USScience for Life Laboratory · SECedars-Sinai Medical Center · US

Funding

VIRAL MALIGNANCYP30CA023100 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jesse Nodora · 1985 to 2026
$124.9M
UC San Diego Clinical and Translational Research InstituteUL1TR001442 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S, HOGARTH, MICHAEL · 2015 to 2024
$88.3M
Resource-based Center for the study of the joint microenvironment in rheumatology (Overall Application)P30AR073761 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHUNG, CHRISTINE B · 2018 to 2022
$3.9M
Rheumatic Diseases Research Training GrantT32AR064194 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GARY S FIRESTEIN, Monica Guma · 2013 to 2026
$3.8M
Intra-Articular Drug Delivery Modulating Immune Cells in Inflammatory Joint DiseaseR01AR081887 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ZHANG, LIANGFANG · 2023 to 2025
$1.8M
Engineered biomaterials modulating inflammatory T cells in rheumatic arthritisF31AR079921 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MCBRIDE, DAVID AMBROSE · 2021 to 2022
$79k
Biomaterial scaffold-assisted drug delivery to modulate acute graft-versus-host-diseaseF31HL164055 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KERR, MATTHEW DAVID · 2022 to 2022
$39k
NCATS NIH HHS UL1 TR001442NCI NIH HHS P30 CA023100NHLBI NIH HHS F31 HL164055NIAMS NIH HHS F31 AR079921NIAMS NIH HHS P30 AR073761NIAMS NIH HHS R01 AR081887NIAMS NIH HHS T32 AR064194
6 · The paper itself

Abstract

Disease-modifying drugs have improved the treatment for autoimmune joint disorders, such as rheumatoid arthritis, but inflammatory flares are a common experience. This work reports the development and application of flare-modulating poly(lactic-

Indexed as

Autoimmune DiseasesLactatesNanoparticlesPolyethylene GlycolsAnimalsCalcitriolCattleCytokinesDendritic CellsImmunityMiceSymptom Flare UpX-Ray MicrotomographyCalcitriolCytokinesLactatesPolyethylene Glycolspoly(lactic acid-ethylene glycol)antigenarthritisdendritic cellsimmunomodulationnanoparticles

Identifiers

PMID38016062
PMCPMC11755865
OpenAlexW4389076193

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.