Evidence map›Paper›PMID 38016059›Full record

ReviewFrontiers in cell and developmental biology2023

The many faces of SIRT6 in the retina and retinal pigment epithelium.

Jie Cheng, Casey J Keuthan, Noriko Esumi

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in cell and developmental biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
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  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jie Cheng *Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Casey J Keuthan *Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Noriko EsumiWilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Johns Hopkins University · USJohns Hopkins Medicine · US

Funding

Wilmer Core Grant for Vision ResearchP30EY001765 · NEI · JOHNS HOPKINS UNIVERSITY · PI Ji Yi · 1985 to 2026
$22.1M
Role of OPA1 in Retinal Ganglion Cell Differentiation and the Pathogenesis of Dominant Optic AtrophyR01EY031714 · NEI · JOHNS HOPKINS UNIVERSITY · PI Donald J. Zack · 2022 to 2026
$2.0M
Molecular Mechanisms Regulating VMD2 ExpressionR01EY016398 · NEI · JOHNS HOPKINS UNIVERSITY · PI ESUMI, NORIKO · 2006 to 2009
$643k
NEI NIH HHS P30 EY001765NEI NIH HHS R01 EY016398NEI NIH HHS R01 EY031714
6 · The paper itself

Abstract

Sirtuin 6 (SIRT6) is a member of the mammalian sirtuin family of NAD

Indexed as

glucose metabolismoxidative stressprotein deacylaseretinaretinal pigment epitheliumSIRT6

Identifiers

PMID38016059
PMCPMC10646311
OpenAlexW4388130124

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.