Evidence map›Paper›PMID 38015847›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Deletion of Vβ3

Cheng Ye, Sadie A Clements, Weihong Gu, Aron M Geurts, Clayton E Mathews, David V Serreze, Yi-Guang Chen, John P Driver

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Advancing Animal Models of Human Type 1 Diabetes.Cold Spring Harbor perspectives in medicine · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Cheng Ye *Department of Animal Sciences, University of Florida, Gainesville, FL 32611.
Sadie A Clements *Division of Animal Sciences, University of Missouri, Columbia, MO 65201.
Weihong GuDivision of Animal Sciences, University of Missouri, Columbia, MO 65201.
Aron M GeurtsDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226.
Clayton E MathewsDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, FL 32610.
David V SerrezeThe Jackson Laboratory, Bar Harbor, ME 04609.ORCID 0000-0001-7614-5925
Yi-Guang ChenDepartment of Pediatrics, Medical College of Wisconsin, Milwaukee, WI 53226.
John P DriverDivision of Animal Sciences, University of Missouri, Columbia, MO 65201.ORCID 0000-0002-6714-3335
University of Missouri · USMedical College of Wisconsin · USUniversity of Florida · USJackson Laboratory · US

Funding

The Jackson Laboratory Center for Precision Genetics: From New Models to Novel TherapeuticsU54OD020351 · OD · JACKSON LABORATORY · PI LUTZ, CATHLEEN M · 2015 to 2019
$10.2M
B-lymphocyte Targeting Therapies for Autoimmune DiabetesR01DK095735 · NIDDK · JACKSON LABORATORY · PI SERREZE, DAVID V · 2013 to 2025
$6.2M
Genetic control of autoimmune diabetes inducing cytotoxic T cellsR21AI130656 · NIAID · UNIVERSITY OF FLORIDA · PI CHEN, YI-GUANG, DRIVER, JOHN · 2018 to 2019
$420k
NIAID NIH HHS R21 AI130656NIDDK NIH HHS R01 DK095735NIH HHS U54 OD020351
6 · The paper itself

Abstract

In both humans and NOD mice, type 1 diabetes (T1D) develops from the autoimmune destruction of pancreatic beta cells by T cells. Interactions between both helper CD4

Indexed as

Diabetes Mellitus, Type 1AnimalsCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesHumansMammary Tumor Virus, MouseMiceMice, Inbred C57BLMice, Inbred NODMice, TransgenicReceptors, Antigen, T-CellReceptors, Antigen, T-Cellendogenous retrovirusMtv3thymic deletiontype 1 diabetes

Identifiers

PMID38015847
PMCPMC10710095
OpenAlexW4389100229

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.